Sökning: "SCOS"

Hittade 4 avhandlingar innehållade ordet SCOS.

  1. 1. Health and Social Determinants Among Boys and Girls in Sweden : Focusing on Parental Background

    Författare :Heidi Carlerby; Katja Gillander Gådin; Anders Knutsson; Eija Viitasara; Ina Borup; Mittuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bullying involvement; discrimination; foreign extraction; gender; WHO-HBSC; intersectional perspective; health risk behaviour; parental background; PSP; SHC; SCOS; socio-demography; mobbning; diskrimination; utländsk härkomst; genus; WHO-HBSC; intersektionalitetsperspektiv; hälsoriskbeteende; föräldrabakgrund; PSP; SHC; SCOS; sociodemografi;

    Sammanfattning : The majority of Swedish boys and girls have good psychosomatic health. Despite that the risk of mental health problems such as nervousness, feeling low and sleeping difficulties has increased steadily in recent decades. LÄS MER

  3. 2. Exploring Change toward Sustainability in Established Business Models

    Författare :Arvid Wahlman; Daniel Kindström; Emelie Havemo; Josefine Rasmussen; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : Sustainability outlines one of the greatest societal challenges of our time. To attain genuine sustainable development on a global level, firms must address unsustainability in their business models; that is, in what they offer to their markets, how they produce and deliver products and services, and how they collect and distribute value. LÄS MER

  4. 3. Rational design of novel cell-penetrating peptides

    Författare :Staffan Lindberg; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Although cell-penetrating peptides (CPPs) have been an active field of research for over 20 years there are still properties such as efficiency and stability that must be improved for CPPs to reach their full potential as delivery vectors.In this thesis two peptides were designed for non-covalent oligonucleotide delivery, in an attempt to overcome two major issues hampering wider use of CPPs, namely low stability and endosomal entrapment. LÄS MER

  5. 4. Characterization of nucleic acid delivery with fatty acid modified cell-penetrating peptide nanoparticle formulations

    Författare :Tõnis Lehto; Ülo Langel; Patrick Midoux; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transfection; gene delivery; oligonucleotide; complexes; non-viral; in vivo; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Recent advances with techniques used for manipulating gene expression have brought us to an era where various gene therapeutic approaches are becoming common therapeutic tools for many previously incurable diseases. The main factor impeding the wider translation of gene therapy is that the active pharmaceutical ingredients used for interfering with gene expression are based on nucleic acids and synthetic oligonucleotides and such molecules do not readily reach their intracellular targets due to their physicochemical properties and therefore they require delivery vectors to cross the cell membrane. LÄS MER