Sökning: "SB-334867-A enteric ganglia"

Hittade 1 avhandling innehållade orden SB-334867-A enteric ganglia.

1. 1. Studies on the effect of orexin on upper gastrointestinal function in rats and man

   Författare :Marcus Ehrström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Orexin A; orexin receptors; SB-334867-A enteric ganglia; enteroendocrine cells; migrating myoelectric complex; nitric oxide; gastric emptying; gastric acid secretion; leptin; insulin;

   Sammanfattning : Aims: To define the morphological localisation of orexin A (OXA) in the gut, and study the effect of endogenous and peripherally administered OXA on fasting small bowel motility, gastric emptying and acid secretion, hormones involved in glucose homeostasis and pharmacokinetic profile of OXA in rats and humans. Methods: The distribution of OXA, orexin receptors 1 and 2 (OX1 R, OX2R), neuronal nitric oxide synthase (nNOS) and various peptides were studied with immunocytochemistry in rat and human gut. LÄS MER