Sökning: "S100A8 A9"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden S100A8 A9.

  1. 1. Studies of in vivo prostate amyloidosis and autoimmune responses towards amyloid structures in neurodegeneration

    Författare :Kiran Yanamandra; Ludmilla Morozova-Roche; Dina Raveh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; amyloidosis; immune reactivity; S100A8 A9; insulin; α-synuclein; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : By using multidisciplinary analysis of CA inclusions in prostate glands of patients diagnosed with prostate cancer, we have revealed that their major components are the amyloid forms of S100A8 and S100A9 proteins associated with numerous inflammatory conditions and types of cancer. We have demonstrated that material closely resembling CA can be produced from S100A8/A9 in vitro and shows the characters of amyloids. LÄS MER

  3. 2. Neutrophil mediators and their receptors in the pathogenesis and prognosis of cardiovascular disease

    Författare :Helena Grauen Larsen; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular disease; Coronary Artery Disease; Inflammation; S100A12; S100A8 A9; sRAGE; IMT; MACE; Mortality; GWAS; rs2070600; Psychological stress;

    Sammanfattning : .... LÄS MER

  4. 3. Studies on anti-dsDNA Antibodies and other potential biomarkers in Systemic Lupus Erythematosus

    Författare :Michele Compagno; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic Lupus Erythematosus Anti-dsDNA antibodies Biomarkers Osteopontin S100A8 A9 LE-cells Diagnostic accuracy Longitudinal study Multicentre study;

    Sammanfattning : Systemic Lupus Erythematosus (SLE) is characterized by chronic inflammation involving many organ systems. The etiology is unknown and the pathogenesis has not been fully elucidated. Impairments of the immune system and of the mechanisms regulating cell death are commonly seen in SLE patients. LÄS MER

  5. 4. Systemic sclerosis. Novel molecular and epidemiological features of disease

    Författare :Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

    Sammanfattning : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. LÄS MER

  7. 5. Different Aspects of Psoriasis : Comorbidity, Comedication and Disease Biomarkers

    Författare :Albert Duvetorp; Oliver Seifert; Jan Söderman; Karin Öllinger; Mats Nilsson; Mona Ståhle; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; calgranulin a; calgranulin b; depression; comedication; biomarkers; NBUVB.;

    Sammanfattning : Psoriasis is a common heterogeneous inflammatory disease with its predominant manifestation occurring in the skin. The impact of this disease, however, extends far beyond the skin surface. LÄS MER