Sökning: "S. pneumoniae"

Visar resultat 41 - 45 av 59 avhandlingar innehållade orden S. pneumoniae.

  1. 41. The antimicrobial role of human MAIT cells

    Författare :Caroline Boulouis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : MAIT cells are unconventional T cells that have characteristics of both innate and adaptive immunity. Their fast mobilization and wide distribution in tissues make them part of the first line of defense against infection. MAIT cells recognize riboflavin-related metabolites produced by bacteria and presented by MR1. LÄS MER

  3. 42. Production and folding of proteins in the periplasm of Escherichia coli

    Författare :Rageia Elfageih; Jan-Willem de Gier; Hans-Georg Koch; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; periplasm; recombinant protein production; disulfide bond containing proteins; translation initiation region; protein translocation machinery; co-translational folding; neuraminidases; biokemi; Biochemistry;

    Sammanfattning : The Gram-negative bacterium E. coli is the most widely used host for the production of recombinant proteins. Disulfide bond containing recombinant proteins are usually produced in the periplasm of E. coli since in this compartment of the cell - in contrast to the cytoplasm - disulfide bond formation is promoted. LÄS MER

  4. 43. Studies on experimental anaerobic infections of the middle ear and on the polymorphonuclear leukocyte function under anaerobic conditions

    Författare :Magnus Thore; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otitismedia; anaerobicbacteria; experimental; nitroimidazoles; antibody; phagocytosis; anaerobiosis;

    Sammanfattning : Despite the clinical importance of anaerobic bacteria in otitis media and the uncertainty regarding the proper treatment of the anaerobic focal infection, few experimental studies focused upon the role of these microorganisms in otitis media have been publis­hed. In the present investigation a guinea-pig model for the induc­tion of anaerobic monoinfections in the middle ear was described. LÄS MER

  5. 44. Antimicrobial peptides in innate immunity : interactions with antibiotics and effects of post-translational modifications

    Författare :Salma Al Adwani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cationic antimicrobial peptides (AMPs) are important innate immunity factors contributing to the clearance of invading pathogens and immunomodulating immune responses. In this thesis, the focus is on AMPs of the cathelicidin family, i.e. the human LL-37 and the canine K9CATH. LÄS MER

  7. 45. Pneumococcal interactions with the host : threats and therapeutic approaches

    Författare :Mario Codemo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae (the pneumococcus) is a Gram-positive bacterium responsible for substantial morbidity and mortality worldwide. Apart from causing severe pneumonia, septicemia or meningitis, pneumococci are also major contributors to less severe diseases like otitis media and sinusitis. LÄS MER