Sökning: "S Stewart"

Hittade 2 avhandlingar innehållade orden S Stewart.

  1. 1. Amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations in British Columbia, Canada : clinical, neurophysiological and neuropathological features

    Författare :Heather G. Stewart; Hiroshi Mitsumoto; Umeå universitet; []
    Nyckelord :ALS; SOD1; complete penetrance; incomplete penetrance; mis-diagnosis; upper motor neuron; clinical neurophysiology; transcranial magnetic stimulation; peristimulus time histogram; corticospinal pathway; cortical inhibition; cortical hyper-excitability;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by loss of motor neurons and their supporting cells in the brain, brainstem and spinal cord, resulting in muscle paresis and paralysis including the bulbar (speech, chewing, swallowing) and respiratory muscles. The average age at onset is 55 years, and death due to respiratory failure occurs 2-5 years after symptom onset in ~ 85% of cases. LÄS MER

  3. 2. Geographic Distribution of Intra-specific Variation in Widespread Eurasian boreo-nemoral Woodland Herbs

    Författare :Torbjörn Tyler; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; kemotaxonomi. Växters fysiologi inte kärlväxter .; Plant genetics; Växtgenetik; morfologi; chemotaxonomy. Physiology of nonvascular plants; Systematisk botanik; taxonomi; phytogeography; morphology; taxonomy; historical biogeography; Systematic botany; allozymes; population differentiation; postglacial migration; genetic variation; geographic variation;

    Sammanfattning : Many woodland plant species have huge distribution areas covering large parts of the Eurasian continent including areas that were glaciated during the last glacial period. In the present thesis, the geographic distribution of variation within such species is investigated and discussed in relation to glacial survival and post-glacial migration, dispersal ability, breeding system and levels of gene-flow between populations and related species, and various methods to measure and analyse genetic variation. LÄS MER