Sökning: "Rrm1"

Hittade 3 avhandlingar innehållade ordet Rrm1.

  1. 1. Pathology of dNTP dysregulation

    Författare :Phong Tran; Andrei Chabes; Erik Johansson; Ola Hammarsten; Umeå universitet; []
    Nyckelord :dNTP metabolism; DNA replication; mutation rate; cancer; heart development; RNR; SAMHD1; Rrm1; Samhd1; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Deoxyribonucleoside triphosphates (dNTPs) are precursors for DNA replication and repair. Mammalian cells have two distinct biosynthesis pathways to supply dNTPs: de novo and salvage pathways. LÄS MER

  3. 2. Characterization of malignant pleural mesothelioma : possibilities for an individualized therapeutic arsenal

    Författare :Adam Szulkin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Less than 50% of malignant mesothelioma patients respond to standard chemotherapy treatment and there is a great need to identify these patients, and find their best treatment options. The aim of this thesis was to increase the understanding of drug sensitivity in malignant pleural mesothelioma. LÄS MER

  4. 3. The Regulation of Human Papillomavirus Type16 Early Gene Expression

    Författare :Xiaoxu Cui; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; splicing; hnRNP D; m6A; LCR;

    Sammanfattning : AbstractHuman papillomaviruses (HPVs) are small non enveloped viruses that contain a double-stranded circular DNA genome of approximately 8kb in size. It has been estimated that approximately 5% of all cancers are caused by HPV infection. Cervical cancer represents the majority of HPV-associated anogenital cancers worldwide. LÄS MER