Sökning: "Rph1"

Hittade 4 avhandlingar innehållade ordet Rph1.

  1. 1. Studies of Budding Yeast Transcription Factors Acting Downstream of Nutrient Signaling Pathways

    Författare :Niklas Nordberg; Hans Ronne; Anders Blomberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Budding yeast; nutrient signaling; glucose repression; aging; caloric restriction; JmjC; histone demethylation; Mig1; Mig2; Mig3; Gis1; Rph1; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Being able to respond to extracellular cues such as nutrients and growth factors is of vital importance to all living cells. Pathways have therefore evolved which can sense the extracellular status, transmit a signal through the cell and affect gene expression, which ultimately enables adaptation. LÄS MER

  3. 2. Genome-wide Studies of Transcriptional Regulation in Yeast

    Författare :Jakub Orzechowski Westholm; Jan Komorowski; Anthony Wright; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Bioinformatik;

    Sammanfattning : In this thesis, nutrient signalling in yeast is used as a model to study several features of gene regulation, such as combinatorial gene regulation, the role of motif context and chromatin modifications. The nutrient signalling system in yeast consists of several pathways that transmit signals about the availability of key nutrients, and regulate the transcription of a large part of the genome. LÄS MER

  4. 3. Short and long-term regulation of autophagy

    Författare :Patricia González-Rodríguez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autophagy is a conserved catabolic pathway triggered by stress conditions in which portions of the cytoplasm, damage organelles, misfolded proteins and intracellular bacteria are delivered and degraded in the lysosome/vacuoles. Thus, an efficient induction and completion of the process is required to ensure a proper homeostasis of the cell. LÄS MER

  5. 4. The return of the nucleus : epigenetic regulation of autophagy

    Författare :Jens Füllgrabe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autophagy is an evolutionary conserved catabolic process activated in response to a variety of cellular stresses, for example nutrient deprivation or chemotherapy. During autophagy, cells engulf parts of their cytplasm in a double-membrane vesicle, where misfolded proteins or damaged organelles are degraded. LÄS MER