Sökning: "Roland Hartmann"
Hittade 2 avhandlingar innehållade orden Roland Hartmann.
1. Lead(II) as a Tool for Probing RNA Structure in vivo
Sammanfattning : Chemical modification and limited enzymatic hydrolysis are powerful methods to obtain detailed information on the structure and dynamics of RNAs in solution. In the work presented here I have taken advantage of the properties of the divalent metal ion lead(II) to establish it as a new probe for investigating the structure of RNA in vivo. LÄS MER
2. Investigation of RNase P active site residues and catalytic domain interaction
Sammanfattning : RNase P is an essential endoribonuclease responsible for the maturation of the tRNA 5’end. The RNase P family encompasses the ribozyme based, RNase P RNP, and proteinaceous RNase P (PRORP). The ribozyme based RNase P is widely distributed in most species while PRORP has so far mainly been found in some eukaryotic cells. LÄS MER