Sökning: "Roderick E. Hubbard"

Hittade 1 avhandling innehållade orden Roderick E. Hubbard.

1. 1. Reducing Attrition via Improved Strategies for Pre-clinical Drug Discovery : SPR-biosensor Aided Interaction Studies

   Författare :Johan Winquist; Helena Danielson; Roderick E. Hubbard; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biokemi; Biochemistry;

   Sammanfattning : The efficacy of a drug is tightly intertwined with its interaction mechanism with the drug target. The mechanism is dependent on the physicochemical and structural characteristics of both target and drug molecule.Drug discovery is plagued by a high attrition rate, whereas in the clinic, a major issue is drug resistance. LÄS MER