Sökning: "Robert Robinson"

Hittade 4 avhandlingar innehållade orden Robert Robinson.

  1. 1. Structural Study of the WH2 Family and Filamin: Implications for Actin Cytoskeleton Regulation

    Författare :Adeleke H. Aguda; Robert Robinson; Lars Rask; Lars Backman; Uppsala universitet; []
    Nyckelord :Biochemistry; Actin; Thymosin; Ciboulot; N-WASP; Filamin; Calponin homology domain; WH2; Protein Crystallography; Biokemi;

    Sammanfattning : Cellular processes like motility, chemotaxis, phagocytosis and morphogenesis are dependent on the dynamic regulation of the actin cytoskeleton. This cytoskeleton system is tightly controlled by a number of diverse actin-binding proteins (ABPs) by various mechanisms described as nucleation, polymerization, capping, severing, depolymerization and sequestration. LÄS MER

  2. 2. The Structural Basis of the Control of Actin Dynamics by the Gelsolin Superfamily Proteins

    Författare :Sakesit Chumnarnsilpa; Robert Robinson; Lars Backman; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Rearrangement of the actin cytoskeleton occurs in a variety of cellular processes and structures and involves a wide spectrum of proteins. Among these, the gelsolin superfamily proteins (GSPs) control actin organization by severing filaments, capping filament ends and bundling filaments. LÄS MER

  3. 3. Structural and Functional Studies of Gelsolin Family Proteins

    Författare :Qing Ma; Robert Robinson; Roger Karlsson; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Structural biology; Strukturbiologi;

    Sammanfattning : The actin cytoskeleton is a complex structure that performs a wide range of cellular functions including: cell locomotion, cytokinesis, chemotaxis, signal transduction and apoptosis. The coordinated assembly and disassembly of actin filaments is controlled by a multitude of proteins (ABPs) in the cell. LÄS MER

  4. 4. The Membrane Proteome : Evolution, Characteristics and Classification

    Författare :Markus Sällman Almén; Helgi Schiöth; Robert Fredriksson; Marc Robinson-Rechavi; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Membrane proteome; molecular evolution; GPCRs; Dispanins; IFITM; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Membrane proteins are found in all kingdoms of life and are essential for cellular interactions with the environment. Although a large research effort have been put into this group many membrane proteins remains uncharacterized, both in terms of function and evolutionary history. LÄS MER