Sökning: "Robert Koivula"

Hittade 1 avhandling innehållade orden Robert Koivula.

1. 1. Lifestyle and glycaemic control before and after the onset of type 2 diabetes

   Författare :Robert Koivula; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Prediabetes; Obesity; Beta-cell Function; Insulin Sensitivity; Physical Activity; Exercise; Diet; Lifestyle; Ectopic Fat; Genetic Epidemiology; Genetic Risk; Biomarker; Precision Medicine;

   Sammanfattning : Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic dysregulation and eventual T2D. LÄS MER