Sökning: "Robert Engqvist"

Hittade 1 avhandling innehållade orden Robert Engqvist.

  1. 1. Syntheses of some tri- and tetracyclic heterocycles containing an indole moiety

    Författare :Robert Engqvist; jan Bergman; Victor Snieckus; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alkaloid; drug development; heterocycles; indole; metabolite; synthesis; X-ray crystallography;

    Sammanfattning : This thesis deals with the development of new synthetic methods leading to fused tri- and tetracyclic heterocycles, many of which have interesting biological activity such as antiviral and DNA intercalating properties. The reactions between isatins and 2-aminobenzylamine in acetic acid can give, depending on the conditions, either complex spirooxindoles or indolo[3,2-c]quinolin-6-ones. LÄS MER