Sökning: "Richard Birgander"
Hittade 3 avhandlingar innehållade orden Richard Birgander.
1. Analysis of ICP pulsatility and CSF dynamics : the pulsatility curve and effects of postural changes, with implications for idiopathic normal pressure hydrocephalus
Sammanfattning : The volume defined by the rigid cranium is shared by the brain, blood and cerebrospinal fluid (CSF). With every heartbeat the arterial blood volume briefly increases and venous blood and CSF are forced out of the cranium, leading to pulsatility in CSF flow and intracranial pressure (ICP). LÄS MER
2. Brain parenchymal fraction in healthy individuals and in clinical follow-up of multiple sclerosis
Sammanfattning : Background Multiple sclerosis (MS) is an autoimmune disease characterised by inflammatory damage to the central nervous system (CNS). Accumulated CNS injury can be quantified as brain atrophy, definable as a reduction in brain parenchymal fraction (BPF). BPF correlate with disability in MS and is used routinely as an endpoint in clinical trials. LÄS MER
3. Cerebral blood flow and intracranial pulsatility studied with MRI : measurement, physiological and pathophysiological aspects
Sammanfattning : During each cardiac cycle pulsatile arterial blood inflates the vascular bed of the brain, forcing cerebrospinal fluid (CSF) and venous blood out of the cranium. Excessive arterial pulsatility may be part of a harmful mechanism causing cognitive decline among elderly. LÄS MER