Sökning: "Richard Birgander"

Hittade 3 avhandlingar innehållade orden Richard Birgander.

  1. 1. Analysis of ICP pulsatility and CSF dynamics : the pulsatility curve and effects of postural changes, with implications for idiopathic normal pressure hydrocephalus

    Författare :Sara Qvarlander; Anders Eklund; Jan Malm; Richard Birgander; Martin U Schuhmann; Umeå universitet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Cerebrospinal fluid; CSF dynamics; Intracranial pressure; Pulse pressure; Normal pressure hydrocephalus; Posture; Predictive tests; Mathematical modelling; Magnetic resonance imaging; Infusion tests;

    Sammanfattning : The volume defined by the rigid cranium is shared by the brain, blood and cerebrospinal fluid (CSF). With every heartbeat the arterial blood volume briefly increases and venous blood and CSF are forced out of the cranium, leading to pulsatility in CSF flow and intracranial pressure (ICP). LÄS MER

  2. 2. Brain parenchymal fraction in healthy individuals and in clinical follow-up of multiple sclerosis

    Författare :Mattias Vågberg; Anders Svenningsson; Richard Birgander; Jonathan Gilthorpe; Anne-Marie Landtblom; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain parenchymal fraction; Neurofilament light; Glial fibrillary acidic protein; Brain atrophy; Multiple Sclerosis; Clinical follow-up;

    Sammanfattning : Background Multiple sclerosis (MS) is an autoimmune disease characterised by inflammatory damage to the central nervous system (CNS). Accumulated CNS injury can be quantified as brain atrophy, definable as a reduction in brain parenchymal fraction (BPF). BPF correlate with disability in MS and is used routinely as an endpoint in clinical trials. LÄS MER

  3. 3. Cerebral blood flow and intracranial pulsatility studied with MRI : measurement, physiological and pathophysiological aspects

    Författare :Anders Wåhlin; Anders Eklund; Jan Malm; Richard Birgander; William G Bradley; Umeå universitet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Arterial Pulsatility; cerebrospinal fluid; cerebral blood flow; venous flow; intracranial pressure; pulse pressure; dementia; hippocampus; multiple sclerosis; magnetic resonance imaging; radiofysik; radiation physics;

    Sammanfattning : During each cardiac cycle pulsatile arterial blood inflates the vascular bed of the brain, forcing cerebrospinal fluid (CSF) and venous blood out of the cranium. Excessive arterial pulsatility may be part of a harmful mechanism causing cognitive decline among elderly. LÄS MER