Sökning: "Ribosomal analysis"

Visar resultat 1 - 5 av 80 avhandlingar innehållade orden Ribosomal analysis.

1. 1. Ribosome and ribosomal RNA Structure : An experimental and computational analysis of expansion segments in eukaryotic ribosomal RNA

   Författare :Gunnar Alkemar; Odd Nygård; Anders Virtanen; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; eukaryotes; expansion segment; ribosomes; rRNA; secondary structure; structure of rRNA.; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

   Sammanfattning : Ribosomes are large ribonucleoprotein complexes which incorporate amino acids into peptide chains during translational process in all types of living cells. The eukaryotic ribosome is larger compared to its prokaryotic counterpart. LÄS MER

3. 2. Ribosomal translocation in real time : Method development to Applications

   Författare :Chang-il Kim; Suparna Sanyal; Martin Ott; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ribosome; EF-G; pyrene mRNA; aminoglycoside; ribosomal protein; GTP hydrolysis; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : Translational elongation is the process in which the ribosome adds one amino acid at a time to the nascent peptide chain. As the ribosome elongates the peptide chain by 14 - 20 amino acids per second and performs hundreds of such cycles per protein, ‘elongation’ is one of the most crucial steps in translation. LÄS MER

4. 3. Structural and Biochemical Studies of Antibiotic Resistance and Ribosomal Frameshifting

   Författare :Yang Chen; Maria Selmer; Dominique Fourmy; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; elongation; elongation factor G; fusidic acid; antibiotic resistance; aminoglycoside adenyltransferase; ribosomal frameshifting; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

   Sammanfattning : Protein synthesis, translation, performed by the ribosome, is a fundamental process of life and one of the main targets of antibacterial drugs. This thesis provides structural and biochemical understanding of three aspects of bacterial translation.Elongation factor G (EF-G) is the target for the antibiotic fusidic acid (FA). LÄS MER

5. 4. Phosphoproteomic analysis of Arabidopsis thaliana ribosomes

   Författare :Hanna Klang Årstrand; Alexander Vener; Cornelia Spetea Wiklund; Ingemar Rundquist; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : Ribosomes serve as the site of protein synthesis in all living cells. Ribosomes were discovered in 1955 by George E. Palade when he was studying the endoplasmic reticulum which is covered by ribosomes. He received the Nobel Prize in Physiology or Medicine in 1974 for this discovery. LÄS MER

7. 5. Ribosomal proteins L5, L15 and elongation factor 2, three vital components of the translation machinery : Functional features of RPL5, RPL15 and EF2 from Saccharomyces cerevisiae studied in vivo

   Författare :Hossein Moradi; Roger Karlsson; Odd Nygård; Anders Liljas; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Ribosomal protein; Elongation factor; Translation; Cell Biology; cellbiologi;

   Sammanfattning : Protein synthesis is an essential, energy consuming and tightly regulated process in all living cells. A central core of the cellular protein-factory is a macromolecule called ribosome. Ribosomes are composed of ribosomal RNAs (rRNAs) and proteins (RPs). Additional components such as elongation factors (EFs) also contribute to this process. LÄS MER