Sökning: "RhoGTPases"
Hittade 3 avhandlingar innehållade ordet RhoGTPases.
1. A Podocyte view on RhoGTPases and actin cytoskeleton regulation
Sammanfattning : Proteinuria is a hallmark symptom of chronic kidney disease, that if left to persist constitutes a risk for progression of disease. Symptomatic treatment aiming at decreasing proteinuria is therefore standard practice. LÄS MER
2. RhoGTPase Signaling in Cell Polarity and Gene Regulation
Sammanfattning : RhoGTPases are proteins working as molecular switches as they bind and hydrolyze GTP. They are in their active conformation when GTP is bound and are then able to interact with their effector proteins, which relay the downstream signaling. When the GTP is hydrolyzed to GDP, the RhoGTPase is inactivated. LÄS MER
3. The multifunctional GAP protein YopE of Yersinia is involved in effector translocation control and virulence
Sammanfattning : The Gram-negative bacterium Yersinia pseudotuberculosis employs a type 3 secretion system (T3SS) to establish infections. The T3SS translocates a diverse set of effector proteins directly into the host cells. LÄS MER