Sökning: "Retrovirus"

Visar resultat 6 - 10 av 46 avhandlingar innehållade ordet Retrovirus.

  1. 6. Targeted gene transfer in the developing central nervous system using viral vectors

    Författare :Simon Stott; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; Medicin människa och djur ; Medicine human and vertebrates ; gene transfer; in utero; neonatal; GDNF; nigrostriatal; dopamine; AAV; retrovirus; neuropsykologi; neurofysiologi;

    Sammanfattning : Dopamine (DA) is a neurotransmitter that plays a fundamental role in many aspects of normal brain function. The majority of DA neurons in the brain reside in one region ? the midbrain ? and project axonal connections to specific areas. One of the main target regions of the DA system is the striatum. LÄS MER

  3. 7. Envelopment of retrovirus and vaccinia virus

    Författare :Kristina Wallengren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Retrovirus; Vaccinia virus; Envelopment; Host proteins; Gag-particles; IMV A17L.;

    Sammanfattning : This thesis describes envelopment of retrovirus and vaccinia virus. Retrovirus envelopment, i.e. budding, occurs from the plasma membrane (PM) of infected cells in an environment that is abundant with cellular proteins. LÄS MER

  4. 8. Activation of retrovirus spikes for membrane fusion

    Författare :Robin Löving; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Retroviruses are enveloped viruses that use reverse transcriptase to convert their RNA genome into DNA which is integrated into the host DNA. They enter into the cell by a membrane fusion process. In this the viral membrane fuses with that of the cell so that the internal capsid of the virus with the genome can be released into the cell cytoplasm. LÄS MER

  5. 9. Gene Expression in the Brains of Two Lines of Chicken Divergently Selected for High and Low Body Weight

    Författare :Sojeong Ka; Finn Hallböök; Tom Porter; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chicken; juvenile body weight; divergent selection; gene expression; DNA microarray; quantitiative RT-PCR; hypothalamus; neural plasticity; melanocortin system; endogenous retrovirus; carnitine palmitoyltransferase-1b; Neurobiology; Neurobiologi; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Sammanfattning : Artificial divergent selection of chickens for high and low body weight at 8 weeks of age has produced two lines: the high (HWS) and low (LWS) body weight chicken lines. In addition to the difference in body weight, the lines show extreme differences in feeding behaviour and body composition. LÄS MER

  7. 10. Retroviral and related nucleic acid processing enzymes expression and detection : Applications on clinical studies of HIV and HERVs

    Författare :Raymond Awad; Amnon Hizi; Uppsala universitet; []
    Nyckelord :Medical sciences; Reverse transcriptase; endogenous retrovirus; deoxycytidine kinase; HIV; HERVS; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medical Virology; medicinsk virologi;

    Sammanfattning : Reverse transcriptase (RT), the expression and detection of the enzyme marking the family Retroviridae, has been studied. A new RT activity assay adapted to 96-well microtitre plates is described. It uses a non- radioactive bromodeoxyuridine triphosphate (BrdUTP) substrate in a solid phase format. The assay was highly sensitive. LÄS MER