Sökning: "Resting membrane potential."
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Resting membrane potential..
1. Cellular electrophysiological modulation in chronic atrial fibrillation - Studies with magnesium and GIK solution
Sammanfattning : Although chronic atrial fibrillation (CAF) is the most common sustained cardiac arrhythmia in man, the mechanisms involved in its progressive course are still not fully understood. Recent studies have verified an electrical remodelling of the atrial myocardium that may be responsible for the electrophysiological disturbances known to exist in the fibrillating atria. LÄS MER
Sammanfattning : Epstein-Barr virus (EBV) is a ubiquitous human herpes virus which infects more than 90% of individuals in the population and is causally implicated in lymphoid and epithelial malignancies. Virus invades oropharyngeal mucosa and establishes latency in memory B lymphocytes. LÄS MER
Sammanfattning : The overall aim of the present thesis is to clarify the control of intracellular chloride homeostasis in central neurons, because of the critical role of chloride ions (Cl–) for neuronal function. Normal function of the central nervous system (CNS) depends on a delicate balance between neuronal excitation and inhibition. LÄS MER
4. Effects pf hypoxia and antiepileptic drugs of electrophysiological properties of CA1 neurons in hippocampus
Sammanfattning : This thesis is based on three experimental studies (I-III) of CA1 hippocampal neurons in rat brain slices, where the electrophysiological properties are examined with patch clamp technique under hypoxic conditions and during treatment with antiepileptic drugs, respectively. The cells were visualized and identified in the slice by means of infrared differential interference contrast (IR-DIC) video microscopy and the experiments were carried out at room temperature (22-25 ºC). LÄS MER
5. Neuromodulation within a spinal locomotor network : Role of metabotropic glutamate receptor subtypes
Sammanfattning : The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and their signal pathways. LÄS MER