Sökning: "Resonance assignment"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Resonance assignment.

  1. 1. Structure determination of ribosomal proteins and development of new methods in biomolecular NMR

    Författare :Magnus Helgstrand; KTH; []
    Nyckelord :nuclear magnetic resonance; structure determination; ribosomal proteins; NMR simulations; NMR theory; NMR assignment software; semiautomatic assignment;

    Sammanfattning : This thesis concerns different areas of biomolecular nuclearmagnetic resonance spectroscopy (NMR). In the first part of thethesis a new formalism for simulations of NMR pulse sequencesis introduced. The formalism is derived both from classicalmechanics and quantum mechanics and is presented forhomonuclear and heteronuclear spin systems. LÄS MER

  3. 2. Structural and dynamical basis of NusA´s role in transcription-coupled DNA repair

    Författare :Damasus Okeke; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Resonance assignment; DNA repair; transcription-repair coupling factors; transcription-coupled repair; NusA; DinB; UvrD; autoinhibition; DNA substrate; dynamics.;

    Sammanfattning : DNA repair processes involves a host of repair machineries that are able to recognize and repair the damaged DNA. Nucleotide excision repair (NER) pathway is one of these processes exploited by cells to remove bulky DNA lesions. LÄS MER

  4. 3. Electron Paramagnetic Resonance Studies of Point Defects in AlGaN and SiC

    Författare :Xuan Thang Trinh; Nguyen Tien Son; Erik Janzén; Mary Ellen Zvanut; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Point defects in semiconductor materials are known to have important influence on the performance of electronic devices. For defect control, knowledge on the model of defects and their properties is required. LÄS MER

  5. 4. Protein production, characterization and structure determination in structural genomics

    Författare :Esmeralda A. Woestenenk; Torleif Härd; Göran Karlsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; protein production; protein solubility; fusion tags; nuclear magnetic resonance; structure determination; Biologi; Biology; Biologi;

    Sammanfattning : This thesis covers the process from expression of a heterologous gene in Escherichia coli to structure determination of a protein by nuclear magnetic resonance (NMR) spectroscopy. The first part concerns structural genomics-related parallel screening studies on the effect of fusion tags (in particular the His tag) on protein solubility and the use of fusion tags in fast, parallel purification protocols intended for initial biophysical characterization of human proteins produced in E. LÄS MER

  7. 5. Coding to cure : NMR and thermodynamic software applied to congenital heart disease research

    Författare :Markus Niklasson; Patrik Lundström; Malin Lindqvist Appell; Björn Wallner; Katja Petzold; Malmendal Anders; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Regardless of scientific field computers have become pivotal tools for data analysis and the field of structural biology is not an exception. Here, computers are the main tools used for tasks including structural calculations of proteins, spectral analysis of nuclear magnetic resonance (NMR) spectroscopy data and fitting mathematical models to data. LÄS MER