Sökning: "Reshma Sundar"

Hittade 1 avhandling innehållade orden Reshma Sundar.

1. 1. TRAF6, a key regulator of TGFβ-induced oncogenesis in prostate cancer

   Författare :Reshma Sundar; Marene Landström; Carl-Henrik Heldin; Petra Knaus; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TβRI; TGFβ; TACE; TRAF6; PS1; PKCζ; TβRI-ICD; NICD; Smad; non-Smad; prostate cancer; Snail1; MMP; p300; p21; PAI1; ubiquitination; cleavage; ICD; invasion; HES1; signaling; patologi; Pathology;

   Sammanfattning : Prostate cancer is the most common cancer in men, with the incidence rapidly increasing in Europe over the past two decades. Reliable biomarkers for prostate cancer are currently unavailable. Thus, there is an urgent need for improved biomarkers to diagnose prostate cancer at an early stage and to determine the best treatment options. LÄS MER