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Visar resultat 1 - 5 av 27 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Anatomical, neurochemical and behavioural consequences of immunotoxin lesions of the basal forebrain cholinergic system

   Författare :Giampiero Leanza; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural transplantation; reinnervation; axon growth; functional sparing; memory; learning; cortex; hippocampus; immunolesion; acetylcholine; basal forebrain; rat; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; Physiology; Fysiologi;

   Sammanfattning : The cholinergic hypothesis of geriatric memory dysfunction suggests that the learning and memory deficits representing the cardinal symptoms of dementia in the aged and in patients suffering from Alzheimer's disease may be attributable to a decline in the function of the cholinergic projection systems of the basal forebrain. Although many studies have addressed the issue of a causal relationship between cholinergic hypofunction and cognitive disturbance, analyses of the functional role of the basal forebrain cholinergic neuronal systems in the brain have so far been hampered by the lack of an efficient and specific cholinergic neurotoxin. LÄS MER

3. 2. Cholinergic mechanisms in skeletal muscle : effects of denervation and reinnervation

   Författare :Håkan Askmark; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

4. 3. On transplantation of fetal ventral mesencephalon with focus on dopaminergic nerve fiber formation

   Författare :Nina Törnqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :VM; graft; Parkinson s disease; graft reinnervation; striatum; patchy; intraocular transplantation; intracranial transplantation; primary culture;

   Sammanfattning : Poor cell survival and striatal reinnervation are two of the postulated limiting factors of fetal ventral mesencephalic (VM) grafting in Parkinson's disease. It has, however, been reported that an increased survival of VM dopaminergic neurons does not correlate with an enhanced target innervation. LÄS MER

5. 4. Recurrent laryngeal nerve injury

   Författare :Jonas Hydman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Injury to the recurrent laryngeal nerve is accompanied by a poor functional recovery of the target organ, the larynx. For the patient this means impairments of vocal fold mobility and various kinds of voice disorders. LÄS MER

7. 5. Charcot-Marie-tooth disease : muscle morphological and neurophysiological aspects

   Författare :UllaBritt Ericson-Gripenstedt; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Charcot-Marie-Tooth disease (CMT) is a common inherited disorder of the peripheral nervous system characterised by distal weakness and muscular atrophy, sensory disturbance of the distal limbs, diminished or absent deep tendon reflexes and often pes cavus. CMT is divided into two major groups based on clinical and electrophysiological findings. LÄS MER