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Visar resultat 1 - 5 av 254 avhandlingar som matchar ovanstående sökkriterier.
1. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease
Sammanfattning : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. LÄS MER
2. Regulatory Factors that Reveal Three Distinct Adipocytes : The Brown, the White and the Brite
Sammanfattning : Adipose tissues have long been considered to derive from a common origin. Even the functionally different brown and white adipose tissues were generalized to share a common origin. Brown adipose tissue is a highly innervated and vascularised tissue containing multilocular and multimitochondrial brown adipocytes. LÄS MER
3. Regulatory Immune Responses and Repair Mechanisms in Atherosclerosis
Sammanfattning : Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid rich plaques in the arterial wall. Rupture of a plaque results in clinical manifestations such myocardial infarction or stroke. LÄS MER
4. Regulatory properties of dendritic cells and B cells in adaptive immunity
Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER
5. T Regulatory Cells – Friends or Foes?
Sammanfattning : T regulatory cells (Tregs) have been extensively studied in patients with cancer or autoimmunity. These cells hamper the immune system’s ability to clear tumor cells in cancer patients. In autoimmune diseases, on the other hand, they are not able to restrain autoreactive immune responses. LÄS MER