Sökning: "Regulation 3 58"
Visar resultat 6 - 10 av 17 avhandlingar innehållade orden Regulation 3 58.
6. Endothelin and nitric oxide in coronary vascular regulation with special reference to myocardial ischemia/reperfusion injury
Sammanfattning : The vascular endothelium plays an important role in the regulation of cardiovascular function by producing bioactive substances such as nitric oxide (NO) and endothelin-I (ET- 1). Recent evidence has revealed that endothelial dysfunction is closely related to myocardial ischemia/reperfusion injury. LÄS MER
7. Complex disease genetics : Utilising targeted sequencing and homogeneous ancestry
Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER
8. Small Molecules as Tools in Biological Chemistry : Effects of Synthetic and Natural Products on the Type III Secretion System
Sammanfattning : The increasing use of antibiotics has led to a huge problem for society, as some bacteria have developed resistance towards many of the antibiotics currently available. To help find solutions to this problem we studied small molecules that inhibit bacterial virulence, the ability to cause disease. LÄS MER
9. The relationship between climate, disease and coffee yield: optimizing management for smallholder farmers
Sammanfattning : Climate change and diseases are threatening global crop production. Agroforestry systems, which are characterized by complex multispecies interactions, are considered to provide nature-based solutions for climate change mitigation and pest and disease regulation. LÄS MER
10. Prognostic and biological implications of epigenetic changes in leukemia
Sammanfattning : The field of epigenetic research in hematology and oncology is rapidly expanding. Even so, reliable data linking epigenetic changes to clinical outcomes are scarce. We conducted two retrospective studies in AML. LÄS MER