Sökning: "Regulating factors"

Visar resultat 6 - 10 av 427 avhandlingar innehållade orden Regulating factors.

  1. 6. Transcription factors regulating the immunoglobulin heavy chain locus

    Författare :Tove Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The immunoglobulin heavy (IgH) chain locus is subject to somatic recombination and changes in gene expression in B lineage cells. Enhancers located in the 3' end of the locus may in part regulate these events. This work aimed at increasing the understanding of the function of one of these elements, the HS1,2 enhancer. LÄS MER

  2. 7. Neurotrophic factors and neuronal plasticity

    Författare :Sten Linnarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The neurotrophic factors were originally discovered because of their ability to rescue neurons during a period of naturally occurring programmed cell death. This gave rise to the neurotrophic factor hypothesis which states that specific target-derived factors protect and support subpopulations of innervating neurons, thereby regulating the pattern and quantity of innervation properly for each target tissue. LÄS MER

  3. 8. Prognostic and predictive factors in laryngeal cancer treated with radiotherapy

    Författare :Hedda Haugen; Göteborgs universitet; []
    Nyckelord :Laryngeal cancer; accelerated radiotherapy; predictive factors; pre-radiotherapy hemoglobin level; MVD; p53; Ki-67; EGFr; histopathologic differentiation.;

    Sammanfattning : Radiotherapy (RT) and surgery are the only two curative treatments for patients with laryngeal cancer (LC). RT has the advantage that it offers a possibility to preserve a functioning larynx and hence a functioning normal voice. The response of tumors to RT is heterogeneous, even within the same tumor stage. LÄS MER

  4. 9. Inflammatory transcription factors in atherosclerosis

    Författare :Wolfgang Dichtl; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : Transcription factors such as nuclear factor-kB (NF-kB), activator protein-1 (AP-1) and peroxisome proliferator-activated receptors (PPARs) may play important roles in atherogenesis, by regulating chronic subclinical vascular inflammation. In the first study, we showed that VLDL activates the proinflammatory transcription factor NF-kB in endothelial cells both in vitro and in vivo. LÄS MER

  5. 10. Factors regulating transcription and translation of the mammalian mitochondrial genome

    Författare :Ann Mutvei; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER