Sökning: "Regional cerebral blood flow"
Visar resultat 6 - 10 av 60 avhandlingar innehållade orden Regional cerebral blood flow.
6. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia
Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. LÄS MER
7. Endothelium-derived substances and regional hemodynamics in experimental hypertension
Sammanfattning : The spontaneously hypertensive rat (SHR), a model for experimental hypertension, is considered to have similarities with essential hypertension in humans. Differences between SHR and normotensive Wistar Kyoto rats (WKY) in the vascular response to endothelial-derived substances such as nitric oxide (NO) have been intensively studied in vitro. LÄS MER
8. Optimisation and Validation of Dynamic Susceptibility Contrast MRI Perfusion Measurements
Sammanfattning : The studies presented in this thesis concern the optimisation and evaluation of the dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) technique for the assessment of perfusion-related parameters of the brain, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT). Several methodological factors influence these measurements, for example, contrast-agent administration, arterial input function (AIF) registration, choice of deconvolution algorithm and the choice of pulse-sequence parameters. LÄS MER
9. Posture and brain function in dementia. A study with special reference to orthostatic hypotension
Sammanfattning : Orthostatic hypotension (OH) is believed to be an important cause of cerebral hypoperfusion, leading to chronic fatigue, blurred vision, unsteadiness, dizziness and sometimes syncope. It may also result in episodes of confusion, falls and fractures. The coupling between OH and organic dementia is not clear. LÄS MER
10. Methodological Aspects of Single Photon Emission Computed Tomography of the Regional Cerebral Blood Flow
Sammanfattning : .... LÄS MER