Sökning: "Regional cerebral blood flow"
Visar resultat 21 - 25 av 58 avhandlingar innehållade orden Regional cerebral blood flow.
21. Neurodegenerative Biomarkers in Healthy Elderly - with special reference to the preclinical pattern of biological and cognitive markers for Alzheimer’s disease
Sammanfattning : Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. LÄS MER
Sammanfattning : The general aim of this thesis was to study asymmetric activation of the neocortex in normal subjects, using the rCBF technique and different cognitive tasks. The aim was also to study individual and group variations of asymmetric activation, as well as factors pertaining to these variations. The thesis is based on four investigations. LÄS MER
Sammanfattning : This thesis explored the epidemiology of Posttraumatic Stress Disorder (PTSD) and different aspects of the disorder. Firstly, we investigated the lifetime prevalence of traumatic experiences and PTSD in the general adult population in Sweden and evaluated the impact of different trauma types, trauma frequency, and perceived distress. LÄS MER
Sammanfattning : Idiopathic normal pressure hydrocephalus (iNPH) is a disorder of the elderly, defined by slowly progressive impairment of gait and balance, cognitive decline, and incontinence. Disturbance of the cerebrospinal fluid (CSF) dynamics results in ventriculomegaly without intracranial pressure increase. LÄS MER
Sammanfattning : The aim of the studies was to explore fetal circulatory changes relative to development of brain-sparing flow (BSF) in growth-restricted fetuses exposed to acute hypoxic stress, as provoked by uterine contractions during an oxytocin challenge test (OCT).(1) In fetuses with a normal cerebral circulation during basal conditions, signs of an acute hyperperfusion in both the arterial and venous cerebral vascular systems were demonstrated in response to acute hypoxic stress; (2) Fetuses with an already established BSF showed no further ability of brain-sparing during acute hypoxic stress; (3) In venous cerebral vessels of fetuses with established BSF, the flow responses to hypoxic stress were equivocal, indicating different reactions in areas drained by different veins, or a deranged physiological vascular response; (4) Blood flow changes occurred synchronized in the middle and anterior cerebral arteries when fetuses with an intact cerebral circulation were exposed to hypoxic stress; (5) When fetuses with an established BSF showed no further changes in the middle cerebral artery, no changes were found in the anterior cerebral artery either. LÄS MER