Sökning: "Refractoriness"

Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet Refractoriness.

  1. 1. Cellular electrophysiological modulation in chronic atrial fibrillation - Studies with magnesium and GIK solution

    Författare :Max Ingemansson; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Action potential duration; Atrial cycle length; Atrial remodelling; Autonomic nervous system; AV-nodal; Conduction velocity; GIK; Magnesium; Resting membrane potential.; Refractoriness; Atrial fibrillation; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : Although chronic atrial fibrillation (CAF) is the most common sustained cardiac arrhythmia in man, the mechanisms involved in its progressive course are still not fully understood. Recent studies have verified an electrical remodelling of the atrial myocardium that may be responsible for the electrophysiological disturbances known to exist in the fibrillating atria. LÄS MER

  2. 2. Chronic atrial fibrillation in man. Activation, organisation and characterisation

    Författare :Magnus Holm; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ECG spectral analysis; Preferential conduction; Organisation; Conduction velocity; Refractoriness; Mechanisms; Activation pattern; Chronic; Fibrillation; Human; Atrium; Open-heart surgery; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : Chronic atrial fibrillation (CAF), with a prevalence progressively increasing with age, is one of the most common cardiac arrhythmias in man and associated with increased morbidity and mortality. Previous studies have shown that, in animals as well as in man, experimental atrial fibrillation is based on different types and dimensions of intra-atrial electrical re-entry. LÄS MER

  3. 3. Bacterial physiology and its role in antibiotic refractoriness

    Författare :Spyridon Gkotzis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The pathological outcome of a bacterial infection depends on the interplay among the host’s innate defenses, the virulence arsenal of the pathogen and antibiotic treatment strategies. Understanding this interplay will provide mechanistic insights on antibiotic pharmacodynamics and bacterial pathogenesis, and set the stage for the development of novel therapeutic interventions. LÄS MER

  4. 4. Aspects of Complement Activation in Thrombocytopenic Disorders

    Författare :Alexander Åkesson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thrombocytopenia; Complement activation; Complement dysregulation; Thrombotic microangiopathy; Atypical hemolytic uremic syndrome; Platelet transfusion refractoriness;

    Sammanfattning : The complement system is an essential effector of both innate and acquired immune responses. Due to its destructive potential, tight regulation is required. The contribution of complement has been associated with the pathogeneses in a wide range of diseases. LÄS MER

  5. 5. Studies of exercise-induced bronchoconstriction to define protective mechanisms in asthma

    Författare :Johan Bood; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Exercise-induced bronchoconstriction (EIB) occurs in the majority of asthmatics following vigorous exercise. EIB is caused by a loss of water from the airways creating a hyperosmolar environment in the tissue that in turn triggers the release of bronchoconstrictive mediators. LÄS MER