Sökning: "Reduced thyroid hormones"

Visar resultat 11 - 15 av 15 avhandlingar innehållade orden Reduced thyroid hormones.

  1. 11. Developmental exposure to mixtures of persistent environmental pllutants with focus on bone and retinoid system modulations

    Författare :Lubna E Elabbas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Environmental pollution of Arctic regions has evoked a scientific as well as public concern. Arctic Inuit inhabitants consume large amounts of fatty fish and marine mammals and are therefore exposed to levels of environmental toxicants that are suspected to cause adverse health effects. LÄS MER

  2. 12. Studies on the hormonal regulation of bile acid synthesis

    Författare :Thomas Lundåsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The maintenance of a normal turnover of cholesterol is of vital importance, and disturbances of cholesterol metabolism may result in several important disease conditions. The major route for the elimination of cholesterol from the body is by hepatic secretion of cholesterol and bile acids (BAs) into the bile for subsequent fecal excretion. LÄS MER

  3. 13. Studies on PCSK9 in the regulation of cholesterol metabolism

    Författare :Lena Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :aging;

    Sammanfattning : Elevated levels of plasma cholesterol, mainly in low density lipoproteins (LDL), are a major risk factor for coronary heart disease. The level of plasma LDL cholesterol (LDL-C) is largely dependent on the number of hepatic LDL receptors (LDLRs). LÄS MER

  4. 14. Cloning and characterization of canine sulfotransferases

    Författare :Carrie Tsoi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Sulfotransferase; dog; cytosol; cloning; catalytic properties; mutagenesis;

    Sammanfattning : Sulfation generally leads to an increase in hydrophilicity facilitating increased excretion of conjugated molecules. In addition, sulfation has an important role in the synthesis, metabolism and regulation of steroid hormones as well as in the generation of reactive electrophilic forms of mutagenic heterocyclic amines and hydroxymethyl polyaromatic hydrocarbons. LÄS MER

  5. 15. Studies on energy metabolism and body composition of healthy women before, during and after pregnancy

    Författare :Marie Löf; Lena Hulthén; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Current recommendations propose that an entire pregnancy requires an additional amount of energy from the diet equivalent to 335 000 kJ. This figure is mainly based on increases in the basal metabolic rate (BMR) and retention of total body fat (TBF). LÄS MER