Sökning: "RecA"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet RecA.

  1. 1. Intelligent Nucleic Acid Interactions with Peptide Nucleic Acid (PNA) and Recombination Enzyme RecA

    Författare :Pernilla Wittung; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorescence; RecA; homologous recombination; circular dichroism; DNA analogs; -anti-BPDE; spectroscopy; PNA; DNA-protein interactions;

    Sammanfattning : The work presented in this thesis focuses on interactions between nucleic-acids in biological systems, particularly interactions of the promising drug-candidate peptide nucleic acid (PNA), and on protein-DNA intermediates during recombination. Several experimental techniques, mainly circular dichroism and fluorescence spectroscopy, have been used to characterize the interactions of interest. LÄS MER

  3. 2. Aspects of DNA Strand Exchange: Recombination Proteins and Model System Studies

    Författare :Karolin Frykholm; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA strand exchange; cationic liposome; Rad51; Site-Specific Linear Dichroism; RecA; molecular crowding;

    Sammanfattning : DNA recombination is of fundamental importance to all living cells; it is part of the DNA repair machinery and a means to generate genetic diversity. DNA strand exchange, the exchange of strands between homologous DNA molecules, is the central reaction of the recombination process. LÄS MER

  4. 3. DNA-ligand interactions studied by optical spectroscopy

    Författare :Svante Eriksson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DAPI; DNA; RecA; 2-phenylindole; flow linear dichroism; chromatin; -anti-BPDE;

    Sammanfattning : .... LÄS MER

  5. 4. Bacterial DNA repair and molecular search

    Författare :Arvid H. Gynnå; Johan Elf; Stephen Kowalczykowski; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA repair; DNA damage; homologous recombination; homologous repair; recombination; RecA; I-SceI; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Surveillance and repair of DNA damage is necessary in all kinds of life. Different types of DNA damage require different repair mechanisms, but these mechanisms are often similar in all domains of life. The most serious type of damage, double stranded DNA breaks, are for example repaired in conceptually similar ways in both bacteria and eukaryotes. LÄS MER

  7. 5. DNA-protein complexes : experimental studies of structure and interactions in solution

    Författare :Per Hagmar; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA binding domain; methylene blue; flow linear dichroism; recombination protein A; RecA; chromatin structure; recombination; electric linear dichroism; chromatin; glucocorticoid receptor;

    Sammanfattning : .... LÄS MER