Sökning: "Rat Urinary Bladder"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden Rat Urinary Bladder.

  1. 6. Inducible nitric oxide synthase in experimental urinary tract infection

    Författare :Mirjana Poljakovic; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; host defense; cell viability; nitrate; lipopolysaccaride; cytokines; sphingomyelinase; mitogen activator protein kinase; nitric oxide; nitrotyrosine; E. coli; cyclooxygenase; urinary tract infection; prostaglandins; urothelium; bladder; kidney; NADPH diaphorase histochemistry; nitric oxide synthase; vävnadskultur; histokemi; cytokemi; Histologi; tissue culture; histochemistry; cytochemistry; Histology; nefrologi; Urologi; nephrology; Infections; Infektioner;

    Sammanfattning : Urinary tract infection (UTI) is among the most common bacterial infections in humans and the majority are caused by Escherichia coli (E. coli). Abundant evidence indicates that nitric oxide (NO) produced by the inducible NO synthase (iNOS) plays an important role in host defense against infection. LÄS MER

  3. 7. Regulation of inducible nitric oxide synthase - Consequences in experimental models of bladder disease

    Författare :Rebecka Johansson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacy; toxicology; Farmakologi; smooth muscle-myosin heavy chain; Pharmacological sciences; pharmacognosy; farmakognosi; farmaci; actin; BDNF; Rho; aminoguanidine; TNF-alpha; IL-1beta; hypertrophy; differentiation; smooth muscle; bladder; nitric oxide; inducible nitric oxide synthase; toxikologi;

    Sammanfattning : Inducible nitric oxide synthase (iNOS) expression is associated with various pathophysiological conditions in the lower urinary tract. The aims of this thesis have been to investigate the regulation of iNOS in bladder smooth muscle cells and the consequences on neuromuscular regulation, cell growth and differentiation. LÄS MER

  4. 8. Functional studies of purinergic and cholinergic interactions in the rat urinary bladder - Characterization of ATP-evoked urothelial release of acetylcholine

    Författare :Johanna Stenqvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; acetylcholine; urothelium; caveolae; afferents; cystitis;

    Sammanfattning : Functional interplays between different transmitter systems are known to affect the signalling of the micturition reflex arc. The functional implications of many of these interactions, such as between ATP and acetylcholine, have yet to be unravelled. LÄS MER

  5. 9. Functional Models in the Search for Pharmacological Treatment of Urinary Incontinence : The Role of Adrenergic, Cholinergic, and Serotonergic Receptors

    Författare :Ali-Reza Modiri; Karl-Erik Andersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Stress incontinence and overactive bladder are disorders with a common symptom, urinary incontinence, which is a serious medical and social handicap. Several neurotransmitters regulate the function of the lower urinary tract, including noradrenaline, acetylcholine, and serotonin. LÄS MER

  7. 10. lnvestigating intestinal smooth muscle dysfunction in the 6-OHDA rat model of Parkinson's disease

    Författare :Maria del Pilar Murillo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestinal motility; smooth muscle; enteric nervous system; dopamine neurodegeneration;

    Sammanfattning : The neurodegenerative progression of the nigrostriatal pathway in Parkinson’s disease (PD) entails the appearance of motor and nonmotor symptoms. Nonmotor symptoms are common, having a negative impact on the quality of life of patients living with PD. LÄS MER