Sökning: "Radiopharmaceutical technology"

Visar resultat 6 - 10 av 11 avhandlingar innehållade orden Radiopharmaceutical technology.

  1. 6. MRI evaluation and image processing in gel dosimetry. A study of selected MRI properties and image processing in 3D gel dosimetry

    Författare :Peter Magnusson; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; image registering; multi-slice; slice profile; ferrous sulphate; polyacrylamide; 3D volume acquisition; RF field; B1 field; relaxation time; T1; T2; spin-echo; multi-spin-echo; stochastic noise; nonuniformity; SNR; radiologi; tomografi; medicinsk instrumentering; Radiopharmaceutical technology; Radiofarmaceutisk teknik; Physics; Fysik;

    Sammanfattning : Gel dosimetry is a new dosimetry method applied in radiation therapy. Gel dosimeters consist of a radiation sensitive gel, which can integrate absorbed doses from several radiation sources or beams. The dose to the gel can be evaluated by magnetic resonance imaging (MRI), a procedure that is the focus of the present thesis. LÄS MER

  3. 7. Mixed Beam Dosimetry - From Reactor Core to BNCT Patient

    Författare :Per Munck af Rosenschöld; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BNCT; dosimetry; radiotherapy; mixed beam; quality assurance; in vivo dosimetry; Monte Carlo; ionization chamber; foil activation; MCNP; beam quality correction factor; photon transmission.; Nukleärmedicin; radiobiology; Nuclear medicine; radiobiologi; Radiofarmaceutisk teknik; Radiopharmaceutical technology;

    Sammanfattning : Accurate radiation dosimetry is of paramount importance in order to ensure safe delivery of radiotherapy, and for the possibility of meaningful evaluation of clinical trials, as the radiation absorbed dose is correlated to tissue response. The aim of the studies described in this thesis was to investigate and devise novel approaches to mixed beam dosimetry in boron neutron capture therapy (BNCT). LÄS MER

  4. 8. Image Processing for Quantitative Scintillation-Camera Imaging. Application to Radionuclide Therapy

    Författare :Katarina Sjögreen Gleisner; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; 131-I; Clinical physics; SPECT; conjugate-view; volume quantification; activity quantification; image registration; image segmentation; medicinsk instrumentering; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

    Sammanfattning : Individual-based determinations of the absorbed dose in radionuclide therapy largely rely on absolute measurement of the activity distribution and its redistribution over time. Scintillation-camera imaging is the most commonly employed measuring technique, applied in planar or SPECT mode, sometimes in combination with structural images from CT. LÄS MER

  5. 9. Photon Dose Calculations in a Fluence-Based Treatment Planning System: Data Processing, Implementation and Validation

    Författare :Lars Weber; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Nuclear medicine; Radiopharmaceutical technology; Radiofarmaceutisk teknik; Nukleärmedicin; radiobiology;

    Sammanfattning : The accuracy of dose calculations for various aspects of a treatment planning system (TPS) using an energy fluence beam modelling has been evaluated. The investigated TPS uses a beam model, which separates the energy fluence into a number of sources in the treatment head. LÄS MER

  7. 10. Synthesis, Characterisation and Application of 68Ga-labelled Macromolecules

    Författare :Irina Velikyan; Bengt Långström; Mats Bergström; Helmut Maecke; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; 68Ga; 68Ge 68Ga generator; radiolabelling; microwave heating; specific radioactivity; peptide; protein; antibody; oligonucleotide; positron emission tomography; tumour; Kemi; Chemistry; Kemi;

    Sammanfattning : The positron emitting radionuclide 68Ga (T1/2 = 68 min) might become of practical interest for clinical positron emission tomography (PET). The metallic cation, 68Ga(III), is suitable for complexation with chelators, either naked or conjugated with biological macromolecules. LÄS MER