Sökning: "Radical cyclization"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Radical cyclization.
1. Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization
Sammanfattning : This thesis describes how radical cyclization chemistry can be applied for the construction of heterocyclic compounds.In the first part, a series of electron deficient α-phenylselenenylalkenes were prepared via a PhSeCl-addition/HCl-elimination sequence. LÄS MER
2. Radical Cyclization Approaches to Pyrrolidines
Sammanfattning : Five-membered rings are readily prepared by 5-exo-trig radical cyclization. This thesis is concerned with novel methodology for pyrrolidine synthesis. We have synthesised selenium containing radical precursors from aziridines and α-phenylseleno ketones, and cyclized them to 2,4- and 3,4-disubstituted pyrrolidines. LÄS MER
3. Pyrrolidines via Radical Cyclization
Sammanfattning : .... LÄS MER
4. Carbon-Carbon Bond Formation via Radical Cyclization and Transition Metal Catalysis
Sammanfattning : Free radical cyclization methodology has been used extensively in synthesis for manipulation of complex molecules such as alkaloids, terpenes, carbohydrates, peptides and nucleic acids. The methodology has emerged as a result of work by physical organic chemists who determined rate constants for the most common radical reactions used in organic synthesis. LÄS MER
5. Construction of Five-Membered Heterocycles via Radical Cyclization
Sammanfattning : .... LÄS MER