Sökning: "ROS tolerance"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden ROS tolerance.
1. Development of robust cyanobacterial strains for biotechnological applications : Stress tolerance and cell-specific expression in heterocyst-forming cyanobacteria
Sammanfattning : Synthetic biology tools can be used to exploit potential applications of cyanobacteria, promising photosynthetic hosts for production of fuels and chemicals. Specific genetic tools are needed for the development of robust cyanobacterial strains for bioengineering. LÄS MER
2. The oxidative stress response of Francisella tularensis
Sammanfattning : Francisella tularensis is capable of infecting numerous cell types, including professional phagocytes. Upon phagocytosis, F. tularensis resides within the phagosome before escaping into the cytosol to replicate. Phagocytes constitute a hostile environment rich in ROS, which are employed as a means of killing pathogens. LÄS MER
3. Unveiling the protective mechanisms of NOX2-derived ROS against autoimmune diseases
Sammanfattning : Autoimmune diseases, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), pose a significant burden on society, affecting a considerable portion of the global population. Both SLE and RA are known to have a strong genetic component, with shared genetic predispositions such as neutrophil cytosolic factor 1 (NCF1), which encodes for a subunit of NADPH oxidase 2 (NOX2) complex. LÄS MER
4. Oxidative regulation of NCF1 in B cells and mouse models of arthritis
Sammanfattning : Autoimmune diseases (ADs) are chronic pathologies that result from a dysregulation of autoreactive B and T cells leading to autoantibody production and ultimately destruction of self. In paper I, we studied inflammation associated with autoimmunity. LÄS MER
5. Active oxygen involvement in developmental processes in Populus : with emphasis on HipI-superoxide dismutase
Sammanfattning : In plants, oxidative stress is result of disruption of the cellular redox metabolism and is caused by a variety of stress conditions (abiotic and/or biotic). This leads to the induction of several mechanisms that protect against disruption of the redox balance, as well as mechanisms to assist in recovery from toxicity/damage caused by increased cellular levels of reactive oxygen species (ROS). LÄS MER