Sökning: "RNA Polymerase II"

Visar resultat 16 - 20 av 102 avhandlingar innehållade orden RNA Polymerase II.

  1. 16. The Role of the Escherichia coli RNA Polymerase β´Jaw in Transcription

    Författare :Josefine Ederth; Leif A Isaksson; Anne Farewell; Stockholms universitet; []
    Nyckelord :mikrobiologi;

    Sammanfattning : Transcription, the central step in gene expression and regulation, is carried out by the DNA-dependent RNA polymerase (RNAP). Bacterial RNAP is a complex molecular machine in which the network of interacting parts and their movements, including contacts to nascent RNA and the DNA template, are at best partially understood. LÄS MER

  3. 17. The Multifunctional HnRNP A1 Protein in the Regulation of the Cyp2a5 Gene : Connecting Transcriptional and Posttranscriptional Processes

    Författare :Tina Glisovic; Matti Lang; Francoise Raffalli-Mathieu; Lorenz Poellinger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; Cyp2a5; DNA-protein interaction; gene regulation; hnRNP A1; nucleocytoplasmic shuttling; RNA-protein interaction; RNA stabilization; posttranscriptional; transcriptional; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Sammanfattning : The mouse xenobiotic-inducible Cyp2a5 gene is both transcriptionally and posttranscriptionally regulated. One of the most potent Cyp2a5 inducers, the hepatotoxin pyrazole, increases the CYP2A5 mRNA half-life. LÄS MER

  4. 18. An RNA story, from chromatin to protein

    Författare :Davide Maria Trevisan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : RNA functions expand well over just coding for protein effectors. Non-coding RNAs oversee translation, RNA processing, and spatial organization of the cellular space, therefore participating in the regulation of almost any cellular process. To add a further layer of complexity, both coding and non-coding RNAs are extensively modified. LÄS MER

  5. 19. Role of c-Myc in the regulation of rDNA transcription by RNA polymerase I

    Författare :Chiou-Nan Shiue; Anthony Wright; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Ribosomal biogenesis and protein translation are finely coordinated with cell proliferation. All three RNA polymerases Pol I, II, and III are utilized for highly efficient and accurate ribosome production. The transcriptional activity of Pol I has been found to be a key determinant for ribosome biogenesis. LÄS MER

  7. 20. BEN-solo proteins in genome architecture and function

    Författare :Malin Ueberschär; Qi Dai; Mattias Mannervik; Nicola Iovino; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene regulation; transcription; insulators; genome architecture; Polymerase II pausing; chromatin; Drosophila development; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Eukaryotic genomes are organized in a complex manner inside the nucleus of each cell. Chromatin insulators are DNA elements that help to fold the linear DNA fiber in three-dimensional space and partition regulatory gene units. LÄS MER