Sökning: "RGS5"

Hittade 5 avhandlingar innehållade ordet RGS5.

  1. 1. Functions of Pericytes in Ischemic Stroke

    Författare :Michaela Roth; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Pericytes; RGS5; Blood-brain barrier; vascular remodelling; scar formation;

    Sammanfattning : Ischemic stroke remains one of the leading causes of death and disability worldwide, and its burden is predicted to further increase due to the aging population. The only available treatments, thrombolysis or thrombectomy, can only be applied within a limited time window after stroke onset, and thus are applicable only to a small proportion of stroke patients. LÄS MER

  3. 2. Pericytes in Hypoxia and Ischemic Stroke

    Författare :Andreas Enström; Translationell Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pericytes; Ischemic stroke; Hypoxia; Secretome; Transcriptome; RGS5;

    Sammanfattning : Molecular oxygen is essential for most living species. Consequently, hypoxic or ischemic conditions are major cellular stressors and prominent pathological features in ischemic stroke. Stroke is a global health problem and remains the second leading cause of death or disability worldwide. LÄS MER

  4. 3. Pericytes in Neurodegeneration

    Författare :Thomas Padel; Translationell Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pericyte; Parkinson disease; Huntington Disease; PDGF-BB; RGS5;

    Sammanfattning : .... LÄS MER

  5. 4. Studies on pericytes in health and disease

    Författare :Maya Hestnes Nisancioglu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pericytes are the perivascular mural cells of microvessels. They are intimately associated with endothelial cells and communicate with them via direct physical contact or through paracrine signaling pathways. These interactions are important for blood vessel maturation, remodeling, and maintenance. LÄS MER

  7. 5. On angiogenesis modulation

    Författare :Mattias Kalén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During evolution, the transition from unicellular to multicellular organisms required the origin of a transport system capable of interconnecting specialized cells throughout the body of the organism. In higher animals, this route of transportation is the cardiovascular system, which allows gas exchange, and transport of immune cells, hormones, macromolecules, nutrients and waste products. LÄS MER