Sökning: "RANTES"

Visar resultat 6 - 10 av 57 avhandlingar innehållade ordet RANTES.

  1. 6. Experimental autoimmune sialadenitis : studies of immunopathogenesis, cellular signaling and MHC genetics

    Författare :Elwaleed Ibrahim Mustafa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune sialadenitis (EAS), an animal model for Sjogren´s syndrome (SS) in humans, develops spontaneously in certain mouse strains. A major feature of EAS and SS is infiltration of exocrine glands by mononuclear cells (MNC), and functional impairment of predominantly salivary and lachrymal glands leading to mouth and eye dryness. LÄS MER

  3. 7. Studies on co-stimulatory molecules, chemokines and chemokine receptors in neuroimmunological diseases

    Författare :Natalia Teleshova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Multiple sclerosis (MS) and myasthenia gravis (MG) are characterised by activation of T cells directed against self antigens. Such autoreactive T cells are considered to play a central role in destruction of myelin in MS and in damage of neuromuscular junctions in MG. LÄS MER

  4. 8. Modulation of inflammatory mediators during experimental bacterial meningitis

    Författare :Hana Khidir Abdalla; Kristian Riesbeck; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Bacterial meningitis is a worldwide health problem with high morbidity and mortality mainly caused by Haemophilus influenzae, Neisseria meningitidis and Streptococcus pneumoniae. It is an inflammatory disease of the central nervous system (eNS) initiated by cell wall or membrane components from the bacteria. LÄS MER

  5. 9. Studies on the inflammatory response in experimental acute pyelonephritis and its importance for the development of renal scarring

    Författare :Adli Khalil; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute pyelonephritis especially in childhood is a serious and globally common bacterial infection. The infecting microorganism is often derived from the patient's own bowel flora and mainly affects the renal parenchyma and pelvis. LÄS MER

  7. 10. Mucosal immune responses in HIV-1 exposed uninfected individuals

    Författare :Taha Hirbod; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of HIV vaccines and immunotherapeutics remains hampered by our lack of understanding correlates of immune protection to infection and disease. The major (perhaps only) piece of evidence indicating that long-term, solid resistance to HIV infection is indeed possible comes from HIV exposed yet uninfected individuals (EUI). LÄS MER