Sökning: "RANTES"

Visar resultat 21 - 25 av 57 avhandlingar innehållade ordet RANTES.

  1. 21. Innate immunity and cardiac structure in chronic kidney disease

    Författare :Carin Wallquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The inflammatory state of chronic kidney disease (CKD) leads to increased susceptibility to infections and cardiovascular complications. In this thesis we aimed to investigate development of inflammatory properties at different stages of CKD and changes in innate immunity as well as cardiac structure. LÄS MER

  3. 22. Mechanisms of Escherichia coli induced transepithelial neutrophil migration

    Författare :Gabriela Godaly; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; UTI; mucosa; cytokine receptors; inflammation; neutrophils; chemotaxis; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Mucosal infections trigger an inflammatory response that includes the secretion of cytokines and the recruitment of neutrophils to the infected site. This thesis describes studies examining the molecular mechanisms of neutrophil migration to sites of mucosal bacterial infection. Escherichia coli (E. LÄS MER

  4. 23. Experimental bacterial meningitis : studies on immunopathogenesis and immunoregulation

    Författare :Asim Eltayeb Diab; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bacterial meningitis is an inflammatory disease of the central nervous system (CNS) which occurs when bacteria gain entry to the subarachnoid space (SAS). Bacterial replication or Iysis leads to the exposure of cell components. LÄS MER

  5. 24. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

    Författare :Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. LÄS MER

  7. 25. Studies on the efficacy of potent anti-HIV-1 therapy on virological and immunological factors

    Författare :Soo Aleman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to assess to which extent treated human immunodeficiency virus type I (HIV-1) infected patients with a seemingly controlled, defined as undetectable plasma HIV-1 RNA levels (< 50 copies/ml), or low-grade viral replication, exhibited pattems in virological and immunological factors which could suggest a continuation of the disease process. We have therefore analysed the kinetics of HIV-1 DNA levels (Papers I and II), the viral evolution (Paper II), the changes in Beta-chemokine levels (Paper 111) and sCD27 levels (Paper IV), and the appearance of drug resistance associated mutations (Paper V) in such patients. LÄS MER