Sökning: "RAFT"

Visar resultat 11 - 15 av 33 avhandlingar innehållade ordet RAFT.

  1. 11. Distribution of glycosphingolipids in nervous tissue. Immunohistochemical and biochemical studies

    Författare :Marie Molander-Melin; Göteborgs universitet; []
    Nyckelord :Glycosphingolipids; sulfatide; nervous tissue; immunohistochemical analyses; ; biochemical analyses; rafts.;

    Sammanfattning : Glycosphingolipids (GSLs) are highly enriched in cell membranes of the mammalian nervous system. Their biological functions are not clarified although recent findings have supported their existence in plasma membrane domains, enriched in cholesterol, sphingomyelin and GSLs. LÄS MER

  3. 12. Membrane rafts and its GPI anchored complement inhibitors regulate insulin secretion

    Författare :Vini Nagaraj; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Membrane rafts; basal insulin secretion; regulated insulin secretion; CD59; CD55; SNARE proteins; insulin; pancreatic beta cells.;

    Sammanfattning : Type 2 diabetic patients usually exhibit an abnormal lipid profile. One such lipid that is constantly elevated in T2D is cholesterol. At the cellular level, cholesterol aids in tight packing of sphingolipids in certain regions of the plasma membrane and these specialized regions are termed ‘membrane rafts’, which act as signalling hubs. LÄS MER

  4. 13. Deciphering ret signalling in cell biology and development

    Författare :Moritz Lübke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The rearranged during transformation (RET) tyrosine kinase regulates a plethora of biological processes such as cell survival, proliferation and migration and is essential for the normal development of several organs such as the sensory, enteric and sympathetic nervous systems and the kidneys. After RET activation by its ligands several intracellular tyrosine residues are phosphorylated and serve as binding sites for adaptor proteins that activate different downstream signalling pathways. LÄS MER

  5. 14. Surface Modification of Nanocellulose towards Composite Applications

    Författare :Assya Boujemaoui; Anna Carlmark Malkoch; Eva Malmström Jonsson; Julien Bras; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Nanocellulose; surface modification; functionalization; composites; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Nanocelluloses have attracted great interest during recent decades owing to their renewability, abundancy and remarkable physical and mechanical properties. The aim of this work was to investigate new strategies for surface modification and functionalization of nanocelluloses and their subsequent incorporation in polymer-host matrices. LÄS MER

  7. 15. Applications of in situ proximity ligation assays for cancer research and diagnostics

    Författare :Liza Löf; Masood Kamali-Moghaddam; Ulf Landegren; J.Paul Robinson; Uppsala universitet; []
    Nyckelord :Cancer; Diagnostics; Research; Prognostics; Method development; Flow cytometry; Drug delivery; Molekylär medicin; Molecular Medicine;

    Sammanfattning : In the field of cancer research and diagnostics it is crucial to have reliable methods for detecting molecules involved in the disease. New and better methods for diagnostics, prognostics and drug delivery therefore remain a permanent aim. LÄS MER