Sökning: "RAF"

Visar resultat 1 - 5 av 38 avhandlingar innehållade ordet RAF.

  1. 1. Applied bioinformatics for gene characterization

    Författare :Raf M Podowski; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :bioinformatics; gene characterization; text mining; data visualization;

    Sammanfattning : As the vast majority of human protein-encoding genes are now identified, the new challenge placed before life scientists is the determination of the functions of the proteins. Traditionally, intense, directed efforts are applied to decipher the function of a novel protein using laboratory techniques. LÄS MER

  3. 2. Krylov methods for nonlinear eigenvalue problems and matrix equations

    Författare :Giampaolo Mele; Elias Jarlebring; Raf Vandebril; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Numerical Analysis; Numerisk analys;

    Sammanfattning : Nonlinear eigenvalue problems (NEPs) arise in many fields of science and engineering. Such problems are often defined by large matrices, which have specific structures, such as being sparse, low-rank, etc. Like the linear eigenvalue problem, the eigenvector appears in a linear form, whereas the eigenvalue appears in a nonlinear form. LÄS MER

  4. 3. Gespräche in einer Krise : Analyse von Telefonaten mit einem RAF-Mitglied während der Okkupation der westdeutschen Botschaft in Stockholm 1975

    Författare :Gregor von der Heiden; Anita Malmqvist; Liisa Tiittula; Umeå universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; crisis; telephone calls; conversation analysis; pragmatics; linguistics; verbal interaction; negotiation; Red Army Faction; Baader-Meinhof; terrorism; RAF; Swedish history; political violence; West German history; occupation; Krise; Telefongespräche; Gesprächsanalyse; Sprachwissenschaft; verbale Interaktion; Verhandlung; Rote Armee Fraktion; Baader-Meinhoff; Terrorismus; Linksterrorismus; Deutsche Geschichte; Schwedische Geschickte; Okkupation; kris; telefonsamtal; samtalsanalys; lingvistik; verbal interaktion; förhandling; Röda Armé-fraktion; RAF; Baader-Meinhof; terrorism; vänsterterrorism; tyska historia; svensk historia; ockupation; German language; Tyska språket; Germanic languages; Germanistik; Linguistics; Lingvistik; History; Historia; Criminology; Kriminologi; Empirical conflict research; Empirisk konfliktforskning; Linguistics; lingvistik; tyska; German; historia; History;

    Sammanfattning : When crises develop, people are confronted with difficulties beyond those experienced in normal everyday activities.  Due to the perceived threats inherent to such situations, familiar behaviors may prove ineffective, and such attempts can pose dangerous and unpredictable risks. LÄS MER

  5. 4. Affinity protein based inhibition of cancer related signaling pathways

    Författare :Erik Vernet; Torbjörn Gräslund; Antonino Cattaneo; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Affibody; cancer; endoplasmic reticulum retention; EGFR; HER2; IGF-1R; Raf; Ras; Bioengineering; Bioteknik;

    Sammanfattning : Dysregulation of protein activity, caused by alterations in protein sequence, expression, or localization, is associated with numerous diseases. In order to control the activity of harmful protein entities, affinity ligands such as proteins, oligonucleotides or small molecules can be engineered to specifically interact with them to modulate their function. LÄS MER

  7. 5. Ribosome display for selection and evolution of affibody molecules

    Författare :Sebastian Grimm; Per-Åke Nygren; Mike Taussig; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; ribosome display; phage display; combinatorial protein engineering; library; murine IgG1; SATB1; Ras; Raf; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : Affinity proteins are invaluable tools in biotechnological and medical applications. This thesis is about combinatorial protein engineering principles for the generation of novel affinity proteins to purify mouse immunoglobulin, detect a potential cancer marker protein or inhibit a cell proliferation pathway. LÄS MER