Sökning: "Quantitative genetics"
Visar resultat 21 - 25 av 138 avhandlingar innehållade orden Quantitative genetics.
21. Transcriptional biomarkers of toxicity – powerful tools or random noise? : An applied perspective from studies on bivalves
Sammanfattning : Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds of natural or anthropogenic origin. Biological life can for instance respond to chemical stressors by changes in gene expression, and thus, certain gene transcripts can potentially function as biomarkers, i.e. LÄS MER
22. Dissecting the genetics of athletic performance and conformation traits in horses
Sammanfattning : The overall aims of this thesis were to investigate the genetics of athletic performance and the level of inbreeding in Coldblooded trotters, as well as the genetics of conformation traits in Icelandic horses. In paper I, genomic-based inbreeding coefficients in Coldblooded trotters were estimated and compared with pedigree-based coefficients. LÄS MER
23. Genomic selection and genome-wide association studies to dissect quantitative traits in forest trees
Sammanfattning : The convergence of quantitative genetics of complex traits with genomic technologies is quickly becoming an innovative approach to explore fundamental genetic questions and also have practical consequences for implementations in tree breeding. In this thesis, I used genomic selection and genome-wide association studies (GWAS) to dissect the genetic basis of quantitative traits, i. LÄS MER
24. Mapping and functional characterization of candidate genes and mutations for chicken growth : an approach combining computational genetics and bioinformatics
Sammanfattning : Knowledge of the genetics related to growth is important for breeding chickens with the desired traits of rapid and efficient growth. A long-term selection experiment in the domestic chicken (Gallus gallus) has resulted in two highly divergent lines selected for juvenile body weight. LÄS MER
25. Type 2 Diabetes Genes Contributing to Insulin Secretion Defects
Sammanfattning : Type 2 diabetes is caused by a combination of environmental and inherited factors influencing the progression of insulin resistance and impaired insulin secretion leading to chronically elevated blood glucose levels. The aim of this thesis was to functionally and genetically characterise the species-conserved diabetes locus Niddm1i of the GK rat encoding hyperglycaemia and defect insulin secretion. LÄS MER