Sökning: "Quantitative Trait"

Visar resultat 1 - 5 av 122 avhandlingar innehållade orden Quantitative Trait.

  1. 1. Novel Statistical Methods in Quantitative Genetics : Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation

    Författare :Xia Shen; Örjan Carlborg; Lars Rönnegård; William Hill; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; statistical genetics; quantitative trait loci; genome-wide association study; genomic selection; genetic variance; hierarchical generalized linear model; linear mixed model; random effect; heteroscedastic effects model; variance-controlling genes; Complex Systems – Microdata Analysis;

    Sammanfattning : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. LÄS MER

  3. 2. Quantitative Trait Evolution in a Changing Environment in a Seed Beetle

    Författare :Lára R. Hallsson; Mats Björklund; Derek A. Roff; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; quantitative trait; genetic variance; environmental change; temperature; seed beetle; sexual dimorphism; plasticity; inheritance; Animal Ecology; Zooekologi;

    Sammanfattning : During the last decades the climate has been changing more rapidly than in the preceding periods. This is for instance characterized by an increase in temperature. Interestingly, such changes in the environment are not necessarily constant over time as they often show high levels of fluctuation. LÄS MER

  4. 3. Genetic Analysis of Quantitative Traits Using Domestic Animals : A Candidate Gene and Genome Scanning Approach

    Författare :Hee-Bok Park; Leif Andersson; Stefan Marklund; Robert Fredricksson; Holger Luthman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Domestication; horse; pig; chicken; quantitative traits; candidate gene; genome scan; PRKAG3; MC4R; selection experiment; growth; correlated response; metabolic disorders; Quantitative Trait Loci; linkage; single nucleotide polymorphisms; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : Domestication has led to genetic changes that affect quantitative traits in farm animals. Both candidate gene analysis using association tests and genome scans based on linkage analysis have been performed to understand the molecular basis underlying quantitative genetic variation in horses, pigs and chickens. LÄS MER

  5. 4. Adaptive evolution in multidimensional trait spaces

    Författare :Paula Vasconcelos; Claus Rüffler; Maria Servedio; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adaptive dynamics; mutidimensional trait spaces; evolutionary dynamics; disruptive selection; resource competition; diversification;

    Sammanfattning : Negative frequency-dependent disruptive selection, which arises due to the interplay between organisms of a population and their environment, is an important element driving phenotypic diversification and even speciation. Such selection regime can result from frequency- and density-dependent interactions between the organisms and their environment, so that the fitness landscape itself changes as the population evolves. LÄS MER

  7. 5. Genetic and quantitative trait variation in natural bird population

    Författare :Juha Merilä; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER