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1. 1. Promiscuity and Selectivity in Phosphoryl Transferases

   Författare :Alexandre Barrozo; Shina Kamerlin; Qiang Cui; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phosphate chemistry; linear free energy relationships; phosphatase; catalytic promiscuity; empirical valence bond approach; alkaline phosphatase;

   Sammanfattning : Phosphoryl transfers are essential chemical reactions in key life processes, including energy production, signal transduction and protein synthesis. They are known for having extremely low reaction rates in aqueous solution, reaching the scale of millions of years. LÄS MER