Sökning: "QTL Analysis"
Visar resultat 1 - 5 av 52 avhandlingar innehållade orden QTL Analysis.
1. QTL Analysis in the Pig : From the Identification of Quantitative Trait Loci to the Understanding of Molecular Mechanisms
Sammanfattning : Domestic pigs have become very different form the wild ancestors they originate from. Selection for muscle growth and meat quality has made the pig a good model for genetic studies of muscle development.The first part of this thesis presents a genome-wide scan for quantitative trait loci (QTL) in a cross between Landrace and Hampshire pigs. LÄS MER
2. Mitochondrial and chromosomal genomics in type 2 diabetes
Sammanfattning : Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. LÄS MER
3. QTL analysis in heteroscedastic data
Sammanfattning : .... LÄS MER
4. Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference
Sammanfattning : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. LÄS MER
5. Genetic and genomic analysis of arthritis regulating regions in human and mouse
Sammanfattning : Identifying genes involved in the disease pathways of complex diseases such as Rheumatoid arthritis (RA) has been shown to be very difficult. Despite decades of research still only a handful of genes have been convincingly identified as risk genes. LÄS MER