Sökning: "QTL Analysis"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden QTL Analysis.

  1. 1. QTL Analysis in the Pig From the Identification of Quantitative Trait Loci to the Understanding of Molecular Mechanisms

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ellen Markljung; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Domestic pigs have become very different form the wild ancestors they originate from. Selection for muscle growth and meat quality has made the pig a good model for genetic studies of muscle development.The first part of this thesis presents a genome-wide scan for quantitative trait loci (QTL) in a cross between Landrace and Hampshire pigs. LÄS MER

  2. 2. Mitochondrial and chromosomal genomics in type 2 diabetes

    Detta är en avhandling från Lund University

    Författare :Avinash Abhyankar; Lunds universitet.; Lund University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adaptive evolution; nuclear-mitochondrial interaction; linkage analysis; QTL; phylogenetic analysis; congenic; type 2 diabetes; GK rat;

    Sammanfattning : Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. LÄS MER

  3. 3. QTL analysis in heteroscedastic data

    Detta är en avhandling från Lund University

    Författare :Martina Persson; Uppsala universitet.; Uppsala universitet.; [2003]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 4. Two Optimization Problems in Genetics Multi-dimensional QTL Analysis and Haplotype Inference

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Carl Nettelblad; Uppsala universitet.; Uppsala universitet.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantitative trait loci; genome-wide association studies; hidden Markov models; numerical optimization; linkage analysis; haplotype inference; genotype imputation; high performance computing;

    Sammanfattning : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. LÄS MER

  5. 5. Genetic and genomic analysis of arthritis regulating regions in human and mouse

    Detta är en avhandling från Experimentell medicinsk vetenskap

    Författare :Lina Olsson; Lunds universitet.; Lund University.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Immunologi; serologi; transplantation; Skeleton; muscle system; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; QTL; NADPH oxidase complex; Rheumatoid Arthritis; Genetic Analysis;

    Sammanfattning : Identifying genes involved in the disease pathways of complex diseases such as Rheumatoid arthritis (RA) has been shown to be very difficult. Despite decades of research still only a handful of genes have been convincingly identified as risk genes. LÄS MER