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Visar resultat 1 - 5 av 44 avhandlingar som matchar ovanstående sökkriterier.

1. 1. QM/MM free-energy perturbation and other methods to estimate ligand-binding affinities

   Författare :Martin Olsson; Beräkningskemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computer-aided drug design; protein–ligand binding; molecular dynamics; free-energy perturbation; QM MM; convergence;

   Sammanfattning : Experimental drug discovery is very time-consuming, risky and comes at a huge cost, typically several billion USD per drug. Even though decades of experimental drug discovery have provided cures of many diseases, there are still diseases for which there is no effective drug available. LÄS MER

3. 2. Reaction mechanism of metalloenzymes studied by theoretical methods

   Författare :Geng Dong; Beräkningskemi; []
   Nyckelord :Metalloenzymes; Reaction mechanism; QM MM; DFT; DMRG; CAS-srDFT; Big-QM; QTCP;

   Sammanfattning : Metalloenzymes catalyse a wide variety of reactions in nature. In the thesis, I have studied the reaction mechanism of three metalloenzymes, viz. LÄS MER

4. 3. Text Mining The Quality Paradigm(s)

   Författare :Daniel Carnerud; Ingela Bäckström; Kristen Snyder; Ton van der Wiele; Mittuniversitetet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Quality Paradigm; Quality Movement; Quality Revolution; Quality Management; QM; Total Quality Management; TQM; Business Excellence; Text Mining; Data Mining; Kvalitetsparadigm; Kvalitetsrörelsen; Kvalitetsteknik; Offensiv Kvalitetsutveckling; Text Mining; Data Mining;

   Sammanfattning : The purpose of this thesis orbits around an examination of the formation of a quality paradigm. In this inquiry, the exploration and application of text mining have been used to provide new insights into quality as a paradigm. LÄS MER

5. 4. Understanding How to Improve Team Collaboration Within Intensive Care Unit Transitional Care from the Perspective of Quality Management

   Författare :Lilly-Mari Sten; Pernilla Ingelsson; Marie Häggström; Bonnie Poksinska; Mittuniversitetet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ICU; intensive care unit; general ward; team collaboration; nursing science; QM; quality management; quality of care;

   Sammanfattning : Team collaboration is a fundamental part of Quality Management (QM), and working together successfully is an important part of improving an organization. Team collaboration is also essential for achieving quality of care, patient safety and care continuity, especially when handling critically ill patients. LÄS MER

7. 5. A Deeper Understanding of Real Teamwork and Sustainable Quality Culture

   Författare :Lilly-Mari Sten; Pernilla Ingelsson; Marie Häggström; Mattias Elg; Mittuniversitetet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ICU transitional care; QM; quality management; real team; real teamwork; sustainable quality culture; TMT; team; teamwork; top management team;

   Sammanfattning : Today's organisations are faced with increasingly complicated and complex challenges. To master these challenges, organisations need to work more together, both within their own organisations and in collaboration with others. Working as a ‘real’ team, while also creating a sustainable quality culture, can be one way to address these challenges. LÄS MER