Sökning: "Purkinje cell"

Visar resultat 11 - 15 av 25 avhandlingar innehållade orden Purkinje cell.

1. 11. Cerebellar development and very preterm birth interactions with neonatal events

   Författare :Kristbjorg Sveinsdottir; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : AbstractThe cerebellum is an important part of the brain and in very preterm infants the cerebellum is smaller at term equivalent age compared to that of infants born at term.Hypothesis and aims: The general hypothesis is that preterm birth per se causes cerebellar underdevelopment and that certain events following preterm birth, either complications or treatments, can aggravate the underdevelopment. LÄS MER

3. 12. The central cervical nucleus in the rat : studies on connectivity, function and chemical transmission

   Författare :Birger Ragnarson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Amino acid transmitter AMPA Anterograde Cerebellum Cervical Choleragenoid Electron microscopy Freeze-substitution Glutamate Horseradish peroxidase Ia primary afferent Immunogold Immunocytochemistry Locomotion Motoneuron NMDA Neck muscle Postembedding;

   Sammanfattning : The central cervical nucleus (CCN) is a spinocerebellar cell group in the upper cervical spinal cord (rat: Cl-C3), that is known to receive a powerful primary afferent input from, the upper cervical spinal nerves (C 1-C4), originating mainly from muscle spindle afferents in deep dorsal neck muscles and from the ipsi- and contralateral vestibular nuclei. It projects to the cerebellar vermis bilaterally and to all the vestibular nuclei contralaterally. LÄS MER

4. 13. Distribution of glycosphingolipids in nervous tissue. Immunohistochemical and biochemical studies

   Författare :Marie Molander-Melin; Göteborgs universitet; []
   Nyckelord :Glycosphingolipids; sulfatide; nervous tissue; immunohistochemical analyses; ; biochemical analyses; rafts.;

   Sammanfattning : Glycosphingolipids (GSLs) are highly enriched in cell membranes of the mammalian nervous system. Their biological functions are not clarified although recent findings have supported their existence in plasma membrane domains, enriched in cholesterol, sphingomyelin and GSLs. LÄS MER

5. 14. Mechanism of Action of the Antiarrhythmic Agent AZD7009

   Författare :Frida Persson; Göteborgs universitet; []
   Nyckelord :atrial fibrillation; antiarrhythmic drug; IKr; IKur; Ito; IKs; IKACh; INa; ICaL; cardiac action potential; early afterdepolarisation;

   Sammanfattning : Atrial fibrillation (AF) is the most common tachyarrhythmia in the adult population and is a major cause of morbidity and mortality. AF can be terminated and sinus rhythm restored by prolonging the action potential duration (APD) and the refractory period. LÄS MER

7. 15. PDGF in cerebellar development and tumorigenesis

   Författare :Johanna Andræ; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cerebellum; medulloblastoma; PDGF; GFAP; transgenic mice; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Medulloblastoma is a highly malignant cerebellar childhood tumor. As in many other brain tumors, expression of platelet-derived growth factor (PDGF) and its receptors has been shown in medulloblastoma. LÄS MER