Sökning: "Pulmonary surfactants"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Pulmonary surfactants.

1. 1. Solute exhange across the alveolo-capillary barrier

   Författare :Kristina Nilsson; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomography; radiology; Clinical physics; pulmonary oedema.; nuclear medicine; smoking; permeability; rabbit; DTPA; Pulmonary surfactants; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

   Sammanfattning : The aim of this thesis was to study the transfer of solutes across the alveolo-capillary barrier in experimental models of alveolar surfactant dysfunction and lung injury as well as in smokers. Experimental studies were performed in anaesthetized, and mechanically ventilated animals. LÄS MER

3. 2. Initiation of ventilation, surfactant treatment, and lung function after preterm birth

   Författare :Lars Björklund; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Respiration; Artificial; Pediatrics; Pediatri; Respiratory Function Tests; Pulmonary Surfactants; Newborn; Respiratory Distress Syndrome; Infant; Premature; Animals;

   Sammanfattning : The thesis investigates lung function and the effects of rescue surfactant treatment in mechanically ventilated preterm human infants with respiratory distress syndrome (RDS), and the effects of ventilation at birth on the response to surfactant supplementation in preterm lambs. To assess lung function, the author recorded static pressure-volume (P-V) curves during passive deflation from total lung capacity (TLC) to ambient pressure and measured end-expiratory lung volume (FRC) during mechanical ventilation by tracer gas washout. LÄS MER

4. 3. Early ventilatory management and lung function in the immature newly born. Experimental studies in lambs

   Författare :Jonas Ingimarsson; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; Anestesiologi; intensivvård; Anaesthesiology; newborn.; animals; lung recruitment; resuscitation; respiratory distress syndrome; pulmonary surfactants;

   Sammanfattning : Using an animal model, the thesis explores how the initial ventilation of the lungs, and surfactant therapy, should best be managed after premature birth. Material and measurements: The studies were made in newborn lambs delivered by cesarean section. LÄS MER

5. 4. Inactivation of pulmonary surfactant and its prevention

   Författare :Guido Stichtenoth; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Pulmonary surfactant is a lipoprotein complex coating the conducting airways down to the terminal airspaces. Its main function is to lower surface tension at the air liquid interface thus preventing alveolar collapse at end expiration. LÄS MER

7. 5. Development of novel synthetic lung surfactants for treatment of respiratory distress syndrome

   Författare :Oihana Basabe Burgos; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Pulmonary surfactant is a complex mixture of lipids and specific proteins found in the alveoli and its main role is to reduce the surface tension of the alveolar air/water interface, thereby preventing lung collapse. Lack of pulmonary surfactant in premature babies results in lethal respiratory distress syndrome (RDS), which is today treated with surfactant replacement therapy, i. LÄS MER