Sökning: "Pseudomonas aeruginosa"
Visar resultat 21 - 25 av 95 avhandlingar innehållade orden Pseudomonas aeruginosa.
21. On dysregulated inflammation and airway host defense
Sammanfattning : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. LÄS MER
22. Antibiotic resistance and antibiotic consumption with focus on Escherichia coli and Pseudomonas aeruginosa
Sammanfattning : Aims: The general aims of the present studies were to assess the levels of antibiotic resistance, in relation to antibiotic consumption at the Karolinska University Hospital, Solna (KS) and at 11 other Swedish hospitals, furthermore to assess the role of the membrane protein OprD and penicillin-binding proteins in Pseudomonas aeruginosa resistance to imipenem. Methods: Resistance figures were retrieved from the microbiology service databases for the period 1989-99, at the 12 above mentioned hospitals, including their intensive care units (ICU). LÄS MER
23. Studies on Airway Surface Liquid in Connection with Cystic Fibrosis
Sammanfattning : Cystic fibrosis (CF) is one of the most common fatal inherited diseases, most prevalent among Caucasians. CF is caused by a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), which helps to create sweat, digestive juices, and airway surface liquid (ASL). LÄS MER
24. Characterization of IgY for Oral Immunotherapy and Prevention of Pseudomonas aeruginosa Infections in Cystic Fibrosis Patients
Sammanfattning : Chicken antibodies, commonly referred to as IgY, have several properties that make them suitable for oral treatment of infections and there is essentially no risk for development of resistance. The overall aims of this thesis were to investigate Anti-Pseudomonas IgY as prophylaxis against infections with Pseudomonas aeruginosa for cystic fibrosis (CF) patients and to characterize the antibody treatment. LÄS MER
25. FtsH protease and ClpG disaggregase confer fitness advantages to the worldwide prevalent Pseudomonas aeruginosa clone C
Sammanfattning : Pseudomonas aeruginosa is an environmental bacterium and a frequent nosocomial pathogen causing a wide range of opportunistic infections, especially in immunocompromised patients. Clone C is one of the most prevalent groups of closely related strains distributed worldwide in the environment, such as in natural aquatic habitats, and the clinical settings, such as in patients with an underlying functional impairment of the cystic fibrosis transmembrane conductance regulator. LÄS MER