Sökning: "Proteomisk hematologi"

Hittade 1 avhandling innehållade orden Proteomisk hematologi.

1. 1. Molecular and Functional Dynamics of Hematopoietic Progenitor Cell Fate During Ontogeny

   Författare :Maria Jassinskaja; Proteomisk hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hematopoies; developmental hematopoiesis; Proteomics; Leukemia; Mass Spectrometry;

   Sammanfattning : Hematopoietic stem and progenitor cells (HSPCs) in the fetus and the adult possess distinct molecular signatures that regulate cell fate and change their susceptibility to initiation and progression of hematological malignancies, such as leukemia. It is well established that fetal and adult hematopoiesis are functionally distinct processes; however, the underlying molecular mechanisms that govern ontogenic differences in normal and malignant hematopoiesis have thus far been poorly explored on the proteomic level. LÄS MER