Sökning: "Proteoglycans"
Visar resultat 11 - 15 av 144 avhandlingar innehållade ordet Proteoglycans.
11. Retention of atherogenic lipoproteins in atherogenesis
Sammanfattning : Atherosclerosis is the most common cause of death in the industrialized world. The diseaseis characterized by lipid accumulation and inflammation in the arterial wall, which may leadto obstruction of the blood flow. LÄS MER
12. Effects of Asthma Combination Therapy on Extracellular Matrix Remodeling in Human Lung Fibroblasts
Sammanfattning : Fibroblasts, being one of the resident and structural cells of the lung, have the capacity to produce inflammatory mediators, cytokines and extracellular matrix (ECM) proteins perpetuating the inflammation in the airways of asthmatics. Airway remodeling is also a prominent feature of asthma that affects the lung function causing a thickening of the airways. LÄS MER
13. Glypican-1: Structural and functional analysis of the N-glycosylated human protein
Sammanfattning : Glypicans are multifunctional cell surface heparan sulphate proteoglycans co-regulating numerous signalling pathways, and are thereby involved in the control of cellular division, differentiation, and morphogenesis. The heparan sulphate (HS) chains are responsible for many of those biological functions; nevertheless recent studies suggest functional roles for the glypican core proteins in mediating the signalling of various growth factors. LÄS MER
14. Properties of the glomerular endothelial cell surface layer in vitro and in vivo
Sammanfattning : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. LÄS MER
15. Molecular mechanisms of the kidney in health and disease
Sammanfattning : In 2010, 307 Swedish patients received a new kidney through transplantation, and the first of April 2011, 603 patients were on the kidney transplant waiting list. In Sweden over 8000 patients are presently in active uremic care with about half in dialysis and the other half with a functional kidney graft. LÄS MER