Sökning: "Protein-tyrosine phosphatase"
Visar resultat 1 - 5 av 35 avhandlingar innehållade orden Protein-tyrosine phosphatase.
1. Protein tyrosine phosphatase L1 and interacting proteins
Sammanfattning : .... LÄS MER
2. Protein Tyrosine Phosphatases as Regulators of Receptor Ryrosine Kinases
Sammanfattning : Tyrosine phosphorylation is a crucial mechanism in cellular signaling and regulates proliferation, differentiation, migration and adhesion. The phosphorylation reaction is reversible and is governed by two families of enzymes: protein tyrosine kinases and protein tyrosine phosphatases (PTPs). LÄS MER
3. Computer Simulation of Protein Tyrosine Phosphatase Reaction Mechanisms and Dihydrofolate Reductase Inhibition
Sammanfattning : Protein tyrosine phosphatases catalyse the hydrolysis of phosphotyrosine residues in proteins, which is an important reaction in the cell signalling system. The three dimensional structure of such a protein tyrosine phosphatase has been used in a computational study of the reaction mechanism at the atomic level. LÄS MER
4. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway
Sammanfattning : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. LÄS MER
5. The receptor tyrosine kinase Met and the protein tyrosine phosphatase PTPN2 in breast cancer
Sammanfattning : Breast cancer is the most common form of cancer in women worldwide and the second leading cause of cancer death. It is a heterogeneous disease and is subdivided into different subtypes, all with different treatment responses and survival outcomes. LÄS MER