Sökning: "Protein corona"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden Protein corona.

  1. 6. Engineered core : shell nanoparticles: synthesis, characterisation, and biocompatibility studies

    Författare :Carmen Mihaela Vogt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as promising contrast agents for Magnetic Resonance Imaging (MRI). Some SPIONs are already approved for clinical use. Coating of these nanoparticles with an additional biocompatible layer serves to improve the colloidal stability and biocompatibility. LÄS MER

  3. 7. On the Phase Behaviour of Soft Matter: Understanding Complex Interactions via Quantitative Imaging

    Författare :Maxime Bergman; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microgels; Lysozyme; eye lens proteins; confocal microscopy; interaction potential; phase behaviour; simulations;

    Sammanfattning : The effect of microscopic colloid interactions on the resultant macroscopic phase behaviour is a frequently studied topic in soft matter resarch, and lies at the heart of this thesis. Key structural and dynamic properties of colloidal model systems across liquid-solid transitions are tracked using optical imaging techniques. LÄS MER

  4. 8. Enhancing the efficiency of viral and non-viral gene delivery vectors

    Författare :Safa Bazaz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gene therapy, which involves the introduction, alteration, or deletion of genetic material within cells to treat or prevent disease, holds great promise for addressing various genetic disorders and other medical conditions. However, several challenges remain in the field, particularly concerning nucleic acid delivery into target cells. LÄS MER

  5. 9. Dangerous Proteins and Where to Find Them- Structural and functional studies of bacterial and viral proteins interacting with human immune receptors in health and disease

    Författare :Sibel Uzuncayir; Medicinsk strukturbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; immunology; structural biology;

    Sammanfattning : Bacteria and viruses are threats to human that evolved strategies to bypass the immune system and can cause massive damage. Understanding these strategies and elucidating pathogen interacting partners within the human immune system will pave the way for discovery of new medicines and increase human well-being. LÄS MER

  7. 10. Engineering Nanotherapeutic Strategies for Osteoarthritis Treatment

    Författare :Ula von Mentzer; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanoparticles; nanomedicine; cartilage; osteoarthritis;

    Sammanfattning : Osteoarthritis (OA), the most prevalent joint disorder, is characterized by the degeneration of cartilage tissue leading to pain, stiffness, and impaired mobility. Primarily affecting the elderly, OA can also impact athletes, postmenopausal women, and individuals with conditions like diabetes. LÄS MER